2023
DOI: 10.1021/acsabm.3c00083
|View full text |Cite
|
Sign up to set email alerts
|

BODIPY-Based Multifunctional Nanoparticles for Dual Mode Imaging-Guided Tumor Photothermal and Photodynamic Therapy

Abstract: Multifunctional nanoparticles integrating accurate multi-diagnosis and efficient therapy hold great prospects in tumor theranostics. However, it is still a challenging task to develop multifunctional nanoparticles for imaging-guided effective eradication of tumors. Herein, we developed a near-infrared (NIR) organic agent Aza/I-BDP by coupling 2,6-diiodo-dipyrromethene (2,6-diiodo-BODIPY) with aza-boron-dipyrromethene (Aza-BODIPY). Through encapsulating with an amphiphilic biocompatible copolymer DSPE-mPEG5000,… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

0
5
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

citations
Cited by 8 publications
(5 citation statements)
references
References 35 publications
0
5
0
Order By: Relevance
“…Due to the excellent photophysical properties, BODIPYs and aza‐BODIPYs are intensively investigated for a variety of applications ranging from dyes, fluorescent markers and bio‐markers to molecular thermometers and fluorescent viscosity indicators [1–4] . Heavy atom‐containing and organometallic BODIPYs are also studied for their potential applications in photodynamic cancer therapy and optoelectronic materials [5,6] . The relative easiness for the formation of BODIPY core from variety of substituted pyrroles as well as modification of the existing BODIPY core at α‐, β‐, and meso ‐positions allows fine‐tuning of the optical and redox properties of the BODIPY derivatives.…”
Section: Methodsmentioning
confidence: 99%
See 3 more Smart Citations
“…Due to the excellent photophysical properties, BODIPYs and aza‐BODIPYs are intensively investigated for a variety of applications ranging from dyes, fluorescent markers and bio‐markers to molecular thermometers and fluorescent viscosity indicators [1–4] . Heavy atom‐containing and organometallic BODIPYs are also studied for their potential applications in photodynamic cancer therapy and optoelectronic materials [5,6] . The relative easiness for the formation of BODIPY core from variety of substituted pyrroles as well as modification of the existing BODIPY core at α‐, β‐, and meso ‐positions allows fine‐tuning of the optical and redox properties of the BODIPY derivatives.…”
Section: Methodsmentioning
confidence: 99%
“…The relative easiness for the formation of BODIPY core from variety of substituted pyrroles as well as modification of the existing BODIPY core at α‐, β‐, and meso ‐positions allows fine‐tuning of the optical and redox properties of the BODIPY derivatives. The NIR‐absorbing BODIPYs are thought as prominent candidates for light‐harvesting and PDT applications [5,7] . Extension of the conjugated π‐system via Knoevenagel condensation as well as [ a ]‐ and [ b ]‐fusion of aromatic rings to the BODIPY core are the most common strategies for the preparation of NIR‐absorbing BODIPYs [8] .…”
Section: Methodsmentioning
confidence: 99%
See 2 more Smart Citations
“…Aza/I-BDP nanoparticles (NPs) were formed by enclosing them in DSPE-mPEG5000, an amphiphilic biocompatible copolymer. They noticed that the produced NPs showed an amazing photostability, a high quantum yield ( Φ Δ = 59%) of 1 O 2 generation, and good photothermal conversion efficiency 143 (Fig. 21).…”
Section: Utilizing Conjugated Polymers Copolymers and Nanocomposites ...mentioning
confidence: 99%