Body composition assessment in hematopoietic stem cell transplantation

Ueda, Masumi

doi:10.1016/j.bjhh.2017.08.003

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…There are some other factors that affect the GVHD, like body mass index (BMI) which through the decrease before and after HSCT results in the elevated risk of toxicity by conditioning regimens and GVHD 20 and the malnutrition that could have negative effects on the outcome of allogenic HSCT through increasing the risk of GVHD and reducing the survival rate of the patients 21 …”

Section: Graft Vs Host Disease (Gvhd)mentioning

confidence: 99%

“…Higher NRM in obese patients can be due to the higher intensity of conditioning regimens in comparison with normal‐weighted patients 64 . Nutritional status by quantification of albumin and BMI is generally used for evaluation of overall health, and it has been reported that pretransplant BMI < 18.5 kg/m 2 is associated with the higher risk of relapse, the TRM, as well as the lower survival 20 . Regarding the progressive increase in adipose and decrease in muscular tissue during adulthood and the elderly, patients at nutritional risk or poor nutrition status should be recognized, that the best chemotherapy regimens would be decided for them, as these patients are at the risk of chemotherapy‐related toxicity 65 .…”

Section: Survivalmentioning

confidence: 99%

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A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes

Rafiee

Abbasi

Rafieemehr

et al. 2021

Health Science Reports

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Background and aims As a curative procedure, hematopoietic stemcell transplantation (HSCT) is an approved treatment for many malignant orbenign hematologic and non‐hematologic diseases. There are different outcomes of HSCT, as well as several parameters influencing these outcomes. Methods We had searched scientific sources like Web ofScience and PubMed with a combination of keywords such as HSCT, engraftment,survival, outcomes, etc. Totally, 80 articles were included. Results Here we have reviewed the effective factors onmain outcomes of HSCT including engraftment, survival, graft versus hostdisease, and Mobilization. Also, the prediction of hematological reconstitutionand some novel suggestions leading to better outcomes are reviewed. Conclusion The study will be applicable for improvedmanagement of autologous and allogeneic HSCT process to increase the procedureefficiency.

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Section: Graft Vs Host Disease (Gvhd)mentioning

confidence: 99%

Section: Survivalmentioning

confidence: 99%

A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes

Rafiee

Abbasi

Rafieemehr

et al. 2021

Health Science Reports

View full text Add to dashboard Cite

show abstract

Impact of serum albumin and prealbumin as well as anthropometric measurements on long-term survival outcomes after allogeneic stem cell transplantation

El Afifi,

Ali Saad,

El-Ghammaz

et al. 2024

Egypt J Haematol

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Background Allogeneic hematopoietic stem cell transplantation is the treatment of choice for treatment of patients with high-risk features of acute leukemia or those who are relapsed after standard treatment. By now, there are few studies on nutritional assessment of hematological patients before and after hematopoietic stem cell transplantation, and additionally, most rely on one single assessment method. Objective Evaluating nutritional indicators as well as anthropometric measurements in long-term survivors posttransplant, identifying their relationship on transplant outcomes. Patients and methods The present work included 30 patients with two or more years after allogeneic stem cell transplantation who were following up at Bone Marrow Transplantation Unit, Ain-Shams University Hospitals, from January 2019 till January 2023. We assessed nutritional laboratory parameters, including albumin, prealbumin as well as anthropometric measurements, including BMI, waist, circumference, waist–hip ratio, and body fat percentage, using bioelectric impendence in long-term survivors as well as assessment of the quality of life (QoL) using the FACT-BMT questionnaire. Results We found a statistically significant association between nutritional laboratory parameters as well as anthropometric measurements with late transplant outcomes, including the incidence of chronic graft-versus-host disease, disease relapse, and transplant-related mortality as well as posttransplant QoL. Conclusion Nutritional laboratory biomarkers and anthropometric measurements in long-term survivors postallogeneic stem cell transplantation were low-cost, noninvasive biomarkers for early and late transplant complications, patients’ survival, and QoL.

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Body composition assessment in hematopoietic stem cell transplantation

Cited by 2 publications

References 9 publications

A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes

A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes

Impact of serum albumin and prealbumin as well as anthropometric measurements on long-term survival outcomes after allogeneic stem cell transplantation

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