2006
DOI: 10.1079/bjn20061798
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Body composition in patients with chronic obstructive pulmonary disease: which method to use in clinical practice?

Abstract: The objective of the present study was to compare anthropometry with bioelectrical impedance (BIA) in relation to densitometry (dual-energy X-ray absorptiometry; DEXA) as methods of nutritional assessment and body composition in out-patients with chronic pulmonary obstructive disease (COPD). We conducted a cross-sectional clinical study with sixty-one patients with COPD (forty-two men and nineteen women), mean age of 66·5 (SD 7·9) years and forced expiratory volume in 1 s of 1·3 (SD 0·6) litres (52·2 (SD 19·8)… Show more

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Cited by 37 publications
(42 citation statements)
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“…Two reasonable compromises are BIA and DEXA. The amount of FFM assessed by BIA was shown to be lower than with DEXA in patients with COPD (449,451), especially in men (447,449). However, DEXA is not without potential limitation, because it provides systematically higher values for FFM compared with deuterium dilution (450).…”
Section: American Thoracic Society Documentsmentioning
confidence: 99%
See 1 more Smart Citation
“…Two reasonable compromises are BIA and DEXA. The amount of FFM assessed by BIA was shown to be lower than with DEXA in patients with COPD (449,451), especially in men (447,449). However, DEXA is not without potential limitation, because it provides systematically higher values for FFM compared with deuterium dilution (450).…”
Section: American Thoracic Society Documentsmentioning
confidence: 99%
“…The current gold standard is considered by many to be the deuterium dilution technique, but its use is restricted to highly specialized hospital or research centers. Although simple and cheap, skinfold anthropometry generally results in overestimation of FFM compared with other methods (281,447,451). Two reasonable compromises are BIA and DEXA.…”
Section: American Thoracic Society Documentsmentioning
confidence: 99%
“…In the current study, systemic FFM was estimated using bioelectrical impedance measurements, an accurate technique that has been validated and evaluated to assess body composition in patients with COPD (29). Although bioelectrical impedance does not represent a gold standard reference method for measurement of whole body FFM, the estimate of FFM using bioelectrical impedance was used in the National Health and Nutrition Examination Survey III (NHANES III) analysis to identify skeletal muscle cut-off points associated with a high likelihood of physical disability in older subjects and in studies showing the influence of FFM on morbidity and mortality in COPD patients (3,4,30).…”
Section: Discussionmentioning
confidence: 99%
“…Em pacientes com doença pulmonar obstrutiva crônica [88,89] e insuficiência cardíaca [90,91], a bioimpedância vem sendo amplamente utilizada e apresenta alta correlação (r= 0.95; p< 0.001) e confiança (α= 0.98; p< 0.001) quando comparada com método padrão ouro, o dual-energy x-ray absorptiometry (DEXA) [88]. O DEXA é um exame de alto custo, mais completo, que permite além da avaliação da composição corporal, a avaliação da composição mineral e da densidade óssea [88].…”
Section: Análise Microestrutural Muscularunclassified
“…Em pacientes com doença pulmonar obstrutiva crônica [88,89] e insuficiência cardíaca [90,91], a bioimpedância vem sendo amplamente utilizada e apresenta alta correlação (r= 0.95; p< 0.001) e confiança (α= 0.98; p< 0.001) quando comparada com método padrão ouro, o dual-energy x-ray absorptiometry (DEXA) [88]. O DEXA é um exame de alto custo, mais completo, que permite além da avaliação da composição corporal, a avaliação da composição mineral e da densidade óssea [88]. No entanto, este diferencial não fazia parte dos objetivos principais deste estudo, e por isso optou-se por utilizar a BIA, onde os pacientes com HAP apresentaram redução de massa magra e aumento da massa gordurosa, conforme também observado em outras doenças, como DPOC e ICC [92,93].…”
Section: Análise Microestrutural Muscularunclassified