Objective: To describe the prevalence of malnutrition in children and adolescents with cystic fibrosis (CF) at a reference center and to investigate the association between nutritional status, muscular strength and functional capacity in these individuals.Method: Cross-sectional, observational and descriptive study. Malnutrition was defined according to body mass index (BMI) for age, height for age and arm muscle circumference (AMC) percentile. Manovacuometry, dynamometry and the 6-minute walk test (6MWT) were used to evaluate the respiratory and hand grip strength and functional capacity, respectively.Result: A total of 57 patients, aged 13.26±3.1 years, 42.1% of the male gender were evaluated. When evaluating BMI/age, 59.6% of the patients presented nutritional risk and 22.8% were malnourished. Regarding height/age, 15.8% presented short stature for age and according to AMC, 66.7% of the sample showed to be nourished. In the analysis of the association of nutritional status with muscular strength and functional capacity, only a significant difference was observed between nourished and malnourished when nutritional status was evaluated by BMI/age. When comparing the distance walked in 6MWT, hand grip strength, maximum inspiratory pressure and maximum expiratory pressure, according to the categories of the BMI/age percentile, the malnourished walked less distance in 6MWT as well as presented lower values of muscular strength.
Conclusion:The impairment of nutritional status when assessed by the BMI/age index was associated with decreased functional capacity and upper limb muscle strength in children and adolescents with CF.