Body Composition Measurements for Nutrition Research

Coward, W. A.; Parkinson, Susan; Murgatroyd, P. R.

doi:10.1079/nrr19880010

Cited by 37 publications

(22 citation statements)

References 31 publications

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“…Our results demonstrate that combined kidney-pancreas transplantation completely reverts the alterations of amino acid/protein metabolism in diabetic-uremic patients. electrical impedance as previously described ( 16,17). In IDDUP the fat-free mass was assessed at the end of the hemodialytic session ( 17).…”

Section: Introductionmentioning

confidence: 99%

Combined pancreas and kidney transplantation normalizes protein metabolism in insulin-dependent diabetic-uremic patients.

Luzi¹,

Battezzati²,

Perseghin³

et al. 1994

J. Clin. Invest.

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In order to assess the combined and separate effects of pancreas and kidney transplant on whole-body protein metabolism, 9 insulin-dependent diabetic-uremic patients (IDDUP), 14 patients after combined kidney-pancreas transplantation (KPTx), and 6 insulin-dependent diabetic patients with isolated kidney transplant (K-Tx), were studied in the basal postabsorptive state and during euglycemic hyperinsulinemia (study 1). 11-14ClLeucine infusion and indirect calorimetry were utilized to assess leucine metabolism. The subjects were studied again with a combined infusion ofinsulin and amino acids, given to mimic postprandial amino acid levels (study 2). Amol* m-2. min-') (P = NS vs. CON). During hyperinsulinemia (study 1), IDDUP showed a defective decrease of leucine (42% vs. 53%; P < 0.05), BCAA (38% vs. 47%, P < 0.05), ELF (28% vs. 33%, P < 0.05), and LO (0% vs. 32%, P < 0.05) with respect to CON. Isolated kidney transplant reverted the defective inhibition of ELF (34%, P = NS vs. CON) of IDDUP, but not the inhibition of LO (18%, P < 0.05 vs. CON) by insulin. Combined kidney and pancreas transplantation normalized all kinetic parameters of insulin-mediated protein turnover. During combined hyperinsulinemia and hyperaminoacidemia (study 2), IDDUP showed a defective stimulation of NOLD

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Section: Introductionmentioning

confidence: 99%

Combined pancreas and kidney transplantation normalizes protein metabolism in insulin-dependent diabetic-uremic patients.

Luzi¹,

Battezzati²,

Perseghin³

et al. 1994

J. Clin. Invest.

View full text Add to dashboard Cite

show abstract

“…Determination of body composition by underwater weighing is rapid and is precise to within approximately 1%, assuming no error in weight measurement (5). This estimate of precision assumes a 70 kg reference man has 19.3% body fat.…”

Section: Deuterium Oxide Dilutionmentioning

confidence: 99%

“…point out (5). The technique used for the present study quantifies the TBW at the beginning of the equilibration period.…”

Section: Deuterium Oxide Dilutionmentioning

confidence: 99%

“…When safety, flexibility, and precision are considered, this may still be the most reliable index of body composition currently available. Newer techniques are promising (5,18).…”

Section: Deuterium Oxide Dilutionmentioning

confidence: 99%

“…Determination of body composition with this method relies on the same assumptions stated above for body density, with the caveat that deuterium-hydrogen ion exchange in the body will cause the method to overestimate TBW by a quantifiable amount. Precision estimates for D 2 0 dilution techniques have been cited to be as modest as 1-2% (5,15). However, these values actually reflect the variation in quantification of deuterium in the specimens, rather than reproducibility of the technique in humans.…”

Section: Deuterium Oxide Dilutionmentioning

confidence: 99%

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