Body composition, muscle function and biochemical values in patients after pancreatic surgery: An observational study

Petrolo, Martina; Rangelova, Elena; Toilou, M.; Hammarqvist, Folke

doi:10.1016/j.clnu.2021.01.021

Cited by 4 publications

(4 citation statements)

References 34 publications

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“…These divergent results could be attributed to tissue edema from surgical manipulation during abdominal surgery or overall fluid retention post-surgery [27]. A previous study measuring the body composition of patients who underwent pancreatectomy showed an increase in total body water content, especially extracellular weight, after pancreatectomy [28]. In our study, the mean postoperative input-output balance during the immediate postoperative period (POD 0 to 5) was approximately 4 L, which was similar to previous data.…”

Section: Interpretation/comparison With Previous Studiessupporting

confidence: 85%

Body composition assessment using bioelectrical impedance analysis and computed tomography in patients who underwent pancreatoduodenectomy in Korea: a before and after study

Kim,

Hwang

et al. 2023

Ann Clin Nutr Metab

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This study focuses on the need for standardized body composition measurements in the hepatobiliarypancreatic field. It evaluates and compares the effectiveness of bioelectrical impedance analysis (BIA) and computed tomography (CT) scans in assessing body composition of patients undergoing pancreatoduodenectomy (PD), aiming to establish correlations among different body composition indexes. Methods: Ninety-seven patients who underwent PD between August 2022 and March 2023, were enrolled in this study. Muscular and fatty parameters related to BIA and CT were assessed both preoperatively and on postoperative day 6. The correlation between each parameter related to muscle fat was analyzed according to the measurement modalities. Results: There was an increase of skeletal muscle area (SMA), total muscle area, and low attenuated muscle area after surgery. Skeletal muscle mass (SMM) measured using BIA exhibited a strong correlation with the SMA and normal attenuated muscle area (NAMA) measured using CT (r=0.86, P<0.001; r=0.76, P<0.001). The trunk muscle measured using BIA demonstrated moderate to strong correlations with SMA and NAMA measured using CT (r=0.84 P<0.001; r=0.73, P<0.001). Body fat measured using BIA and total fat area (TFA) measured using CT showed strong correlations (r=0.74, P<0.001). In the postoperative analysis, a similar trend was observed (SMM vs. SMA: r=0.80, P<0.001; SMM vs. NAMA: r=0.70, P<0.001), (trunk muscle vs. SMA: r=0.79, P<0.001; trunk muscle vs. NAMA: r=0.69, P<0.001), and (body fat vs. TFA: r=0.83, P<0.001). Conclusion: BIA, akin to CT, serves as a valuable tool for assessing body composition ratios in patients undergoing PD.

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Section: Interpretation/comparison With Previous Studiessupporting

confidence: 85%

Body composition assessment using bioelectrical impedance analysis and computed tomography in patients who underwent pancreatoduodenectomy in Korea: a before and after study

Kim,

Hwang

et al. 2023

Ann Clin Nutr Metab

View full text Add to dashboard Cite

show abstract

“…Newer studies have explored phase angle in surgical settings. Petrolo et al 82 used bioimpedance spectroscopy to measure phase angle in a small sample of patients after pancreaticoduodenectomy or total pancreatectomy. They observed a significant reduction in phase angle in early postoperative days, suggestive of cell loss or reduced cell integrity.…”

Section: Assessing Malnutrition: a Focus On Novel And Nascent Methodsmentioning

confidence: 99%

“…The concurrent decrease in extracellular water was suggestive of an increase in extracellular volume related to a decrease in body cell mass. 82 …”

Section: Assessing Malnutrition: a Focus On Novel And Nascent Methodsmentioning

confidence: 99%

Nascent to novel methods to evaluate malnutrition and frailty in the surgical patient

Prado

Ford

Gonzalez

et al. 2022

J Parenter Enteral Nutr

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Preoperative nutrition status is an important determinant of surgical outcomes, yet malnutrition assessment is not integrated into all surgical pathways. Given its importance and the high prevalence of malnutrition in patients undergoing surgical procedures, preoperative nutrition screening, assessment, and intervention are needed to improve postoperative outcomes. This narrative review discusses novel methods to assess malnutrition and frailty in the surgical patient. The Global Leadership Initiative for Malnutrition (GLIM) criteria are increasingly used in surgical settings although further spread and implementation are strongly encouraged to help standardize the diagnosis of malnutrition. The use of body composition (ie, reduced muscle mass) as a phenotypic criterion in GLIM may lead to a greater number of patients identified as having malnutrition, which may otherwise be undetected if screened by other diagnostic tools. Skeletal muscle loss is a defining criterion of malnutrition and frailty. Novel direct and indirect approaches to assess muscle mass in clinical settings may facilitate the identification of patients with or at risk for malnutrition. Selected imaging techniques have the additional advantage of identifying myosteatosis (an independent predictor of morbidity and mortality for surgical patients). Feasible pathways for screening and assessing frailty exist and may determine the cost/benefit of surgery, long‐term independence and productivity, and the value of undertaking targeted interventions. Finally, the evaluation of nutrition risk and status is essential to predict and mitigate surgical outcomes. Nascent to novel approaches are the future of objectively identifying patients at perioperative nutrition risk and guiding therapy toward optimal perioperative standards of care.

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“…Previous studies had reported that post-operation 1 week loss of lean body mass was significantly greater than the loss of fat mass in gastric cancer patients ( 21 ). Moreover, the changes in water distribution, PA, initial reduced muscle function, and altered biochemical values during the first 9 postoperative days were observed in patients after pancreatic surgery ( 22 ). However, few studies have reported a comparative analysis of body composition changes during surgical treatment in patients with gastrointestinal cancer and non-gastrointestinal cancer, which provide useful information for cancer prognosis and more precise nutritional support.…”

Section: Introductionmentioning

confidence: 99%

Influence of body composition assessment with bioelectrical impedance vector analysis in cancer patients undergoing surgery

Cai,

Luo,

Zhu

et al. 2023

Front. Oncol.

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BackgroundMalnutrition is common in patients undergoing surgery for cancers and is a risk factor for postoperative outcomes. Body composition provides information for precise nutrition intervention in perioperative period for improving patients’ postoperative outcomes.ObjectionThe aim was to determine changes in parameters of body composition and nutritional status of cancer patients during perioperative period.MethodsA total of 92 patients diagnosed with cancer were divided into gastrointestinal and non-gastrointestinal cancer group according to different cancer types. The patients body composition assessed by bioelectrical impedance vector analysis (BIVA) on the day before surgery, postoperative day 1 and 1 day before discharge. The changes between two groups were compared and the correlation between body composition and preoperative serum nutritional indexes was analyzed.ResultsThe nutritional status of all patients become worse after surgery, and phase angle (PA) continued to decrease in the perioperative period. Fat-free mass (FFM), fat-free mass index (FFMI), skeletal muscle mass (SMM), extracellular water (ECW), total body water (TBW), hydration, and body cell mass (BCM) rise slightly and then fall in the postoperative period in patients with gastrointestinal cancer, and had a sustained increase in non-gastrointestinal patients, respectively (P<0.05). Postoperative body composition changes in patients with gastrointestinal cancer are related to preoperative albumin, pre-albumin, hemoglobin, and C-reactive protein (P<0.05), whereas postoperative body composition changes in patients with non-gastrointestinal cancer are related to age (P<0.05).ConclusionsSignificant changes in body composition both in patients with gastrointestinal cancer and non-gastrointestinal cancer during perioperative period are observed. Changes in body composition for the cancer patients who undergoing surgery are related to age and preoperative serum nutrition index.

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Body composition, muscle function and biochemical values in patients after pancreatic surgery: An observational study

Cited by 4 publications

References 34 publications

Body composition assessment using bioelectrical impedance analysis and computed tomography in patients who underwent pancreatoduodenectomy in Korea: a before and after study

Body composition assessment using bioelectrical impedance analysis and computed tomography in patients who underwent pancreatoduodenectomy in Korea: a before and after study

Nascent to novel methods to evaluate malnutrition and frailty in the surgical patient

Influence of body composition assessment with bioelectrical impedance vector analysis in cancer patients undergoing surgery

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