Body Image and Quality of Life in Men With Prostate Cancer

Harrington, Joanne; Badger, Terry A.

doi:10.1097/ncc.0b013e3181982d18

Cited by 33 publications

(43 citation statements)

References 33 publications

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“…Schover et al 22 observed that having a sexual partner was 1 predictor of successful sexual rehabilitation after cancer treatment. An association between changes in body image and quality of life is generally reported after cancer treatments 23 and, in the current study, may particularly have affected survivors with smaller testicular size.…”

Section: Discussionmentioning

confidence: 91%

Sexual function in male long‐term survivors of childhood acute lymphoblastic leukemia

Haavisto

Henriksson

Heikkinen

et al. 2016

Cancer

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BACKGROUND: Infertility, poor semen quality, and gonadal dysfunction are well recognized long-term sequelae in male survivors of childhood acute lymphoblastic leukemia (ALL). However, few studies have investigated adult sexual functioning in these survivors. METHODS: The authors studied 52 male survivors of childhood ALL at a median age of 28.5 years (range, 25-38 years) 10 years after diagnosis. In addition, 56 men without a history of cancer were recruited for an age-matched control group. The participants completed the Derogatis Interview for Sexual Functioning self-report. To analyze predictive factors for sexual dysfunction, variables assessing sociodemographic background, antileukemia treatment, testicular size, laboratory variables from current serum and semen samples, self-reported depressive symptoms, and self-reported physical functioning were included in multiple regression analyses. RESULTS: ALL survivors had significantly poorer sexual functioning, as measured by the Derogatis Interview for Sexual Functioning self-report, compared with the control group. Survivors had a similar frequency of sexual fantasies, autoerotic acts, and full erection during these activities as the control group, but they had less frequent sexual activity with a sexual partner, poorer self-rated orgasms, and lower satisfaction with their sex life. Predictive factors for poorer sexual functioning were depressive symptoms, the absence of a relationship, and, to a lesser extent, testicular size as an indication of gonadal damage from childhood antileukemia therapy. Older survivors experienced a deeper decline in sexual functioning compared with men in the control group. CONCLUSIONS: Decline in sexual functioning at an early adult age can be regarded as 1 of the late effects of childhood cancer. Monitoring these survivors' sexual health is indicated. Cancer 2016;122:2268-76. V C 2016 American Cancer Society.KEYWORDS: childhood leukemia, late effects, long-term survivors, predictive factors, sexual function. INTRODUCTIONLong-term male survivors of childhood acute lymphoblastic leukemia (ALL) are at risk for impaired fertility, poor semen quality, and gonadal dysfunction because of gonadotoxic treatments, such as testicular irradiation and high cumulative doses of cyclophosphamide, used as part of their antileukemia therapy.1-4 The use of prophylactic cranial irradiation as a part of ALL therapy is associated with a risk of anterior pituitary dysfunction. Gonadotropin deficiency is associated with cranial irradiation at doses of >22 grays (Gy). If untreated, it is known to cause increased risk of abdominal obesity, hypertension, dyslipidemia, low bone mineral density, low energy expenditure, and slow walking.5 During the latest decades, cranial irradiation has largely been omitted from the treatment of ALL, 6 and alkylating agents have decreasingly been used. To a certain extent, this has reduced the risks among leukemia survivors. However, few studies have paid attention to adult sexual functioning and its determinants among long...

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Section: Discussionmentioning

confidence: 91%

Sexual function in male long‐term survivors of childhood acute lymphoblastic leukemia

Haavisto

Henriksson

Heikkinen

et al. 2016

Cancer

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“…Selected publications represented five continents and 10 countries including the United States (Stein & Zera , Fobair et al . , Harrington & Badger , Fingeret et al . , , , , Rhoten et al .…”

Section: Resultsmentioning

confidence: 99%

Body image disturbance in adults treated for cancer – a concept analysis

Rhoten

2016

Journal of Advanced Nursing

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This concept analysis provides a foundation for the development of multidimensional assessment tools and interventions to alleviate body image disturbance in this population. A better understanding of body image disturbance in adults treated for cancer will assist nurses and other clinicians in identifying this phenomenon and nurse scientists in developing instruments that accurately measure this condition, along with interventions that will promote a better quality of life for survivors.

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“…Gynaecomastia is particularly problematic. 24,25 Some individuals are less bothered and able to adapt to, or ignore, or in some cases even autoeroticize these feminisation changes. 26 However, most men tend to deal with gynaecomastia by hiding it and this can lead to social isolation.…”

Section: Body Feminisationmentioning

confidence: 99%

Quality of life issues in men undergoing androgen deprivation therapy: a review

Casey¹,

Corcoran²,

Goldenberg³

2012

Asian J Androl

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Androgen deprivation therapy (ADT) has been an essential treatment option for treating prostate cancer (PCa). The role for hormonal treatment initially was restricted to men with metastatic and inoperable, locally advanced disease. Now it has been extended to neoadjuvant or adjuvant therapy for surgery and radiotherapy, for biochemical relapse after surgery or radiation, and even as primary therapy for non-metastatic disease. Fifty percent of PCa patients treated will receive ADT at some point. There is growing concern about the adverse effects and costs associated with more widespread ADT use. The adverse effects on quality of life (QoL), including physical, social and psychological well-being when men are androgen-deprived, may be considerable. This review examines the QoL issues in the following areas: body feminisation, sexual changes, relationship changes, cognitive and affective symptoms, fatigue, sleep disturbance, depression and physical effects. Further suggestions for therapeutic approaches to reduce these alterations are suggested.

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Body Image and Quality of Life in Men With Prostate Cancer

Cited by 33 publications

References 33 publications

Sexual function in male long‐term survivors of childhood acute lymphoblastic leukemia

Sexual function in male long‐term survivors of childhood acute lymphoblastic leukemia

Body image disturbance in adults treated for cancer – a concept analysis

Quality of life issues in men undergoing androgen deprivation therapy: a review

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