Body iron excretion by healthy men and women

Hunt, John; Zito, Carol A; Johnson, LuAnn K.

doi:10.3945/ajcn.2009.27439

Cited by 81 publications

(82 citation statements)

References 17 publications

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“…Under steady state conditions, serum ferritin concentrations correlate well with total body iron stores. Thus, serum ferritin is the most convenient laboratory test to estimate iron stores (Wood et al, 2005;Nadadur et al, 2008;Hunt et al, 2009 levels decreased in blood samples of the subjects after 20 days of taking beetroot in comparison to the levels that have been recorded before the test as in Table 1 and Figure 4 and the decrease percentage was ranged between 1 and 14.3%. The decrease in transferrin level may be as a result of decrease for iron demand.…”

Section: Resultsmentioning

confidence: 99%

Effect of red beetroot (Beta vulgaris L.) intake on the level of some hematological tests in a group of female volunteers

Al-aboud¹

2018

ISABB. J. Food and Agric. Sci.

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The plant kingdom constitutes a source of new chemical compounds which may be important owing to their potential use in medicine and other applications. This study discussed the effect of taking 8 g of beetroot (Beta vulgaris L.) for 20 days on the blood samples of female volunteers where the hemoglobin levels before and after the study was recorded. The results showed mild increase in hemoglobin readings, decrease in total iron binding capacity (TIBC), increase in ferritin and decrease in transferrin. Also, there was mild increase in serum iron levels after taking beetroot. Regarding MCV, it showed mild increase in four volunteers only. However, more research is needed to clearly identify mechanisms of action and proper dosing patterns to maximize the performance benefits of beetroot.

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Section: Resultsmentioning

confidence: 99%

Effect of red beetroot (Beta vulgaris L.) intake on the level of some hematological tests in a group of female volunteers

Al-aboud¹

2018

ISABB. J. Food and Agric. Sci.

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“…A woman's body contains about 3 g of Fe and 80 mg of Cu. After menopause, the daily requirements for Fe and Cu are 1 and 1.6 mg, respectively (Hunt et al, 2009). We assume steady-state (daily requirement cover daily losses) and that the residence times of Fe and Cu in the body can be approximated by the ratio between the metal burden and daily requirement.…”

Section: Discussion Fe and Cu Isotope Composition Of Rbc After Menopausementioning

confidence: 99%

Menopause effect on blood Fe and Cu isotope compositions

Jaouen

Balter

2013

American J Phys Anthropol

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Iron (δ(56) Fe) and copper (δ(65) Cu) stable isotope compositions in blood of adult human include a sex effect, which still awaits a biological explanation. Here, we investigate the effect of menopause by measuring blood δ(56) Fe and δ(65) Cu values of aging men and women. The results show that, while the Fe and Cu isotope compositions of blood of men are steady throughout their lifetime, postmenopausal women exhibit blood δ(65) Cu values similar to men, and δ(56) Fe values intermediate between men and premenopausal women. The residence time of Cu and Fe in the body likely explains why the blood δ(65) Cu values, but not the δ(56) Fe values, of postmenopausal women resemble that of men. We suggest that the Cu and Fe isotopic fractionation between blood and liver resides in the redox reaction occurring during hepatic solicitation of Fe stores. This reaction affects the Cu speciation, which explains why blood Cu isotope composition is impacted by the cessation of menstruations. Considering that Fe and Cu sex differences are recorded in bones, we believe this work has important implications for their use as a proxy of sex or age at menopause in past populations.

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“…The only reliable quantitative data for obligatory iron losses, however, are derived from a single study that estimated an average iron loss of 0.9-1.0 mg/d (14 lg/kg body weight) in men with normal iron status from the United States, Venezuela, and South Africa (1). Whereas there is some support from Bothwell et al (2) for this estimate of daily iron losses per kilogram of body weight, there is a need to evaluate further the extent to which obligatory iron losses vary with ethnicity, age, and sex groups and with iron status (3).…”

Section: Introductionmentioning

confidence: 99%

Iron bioavailability and dietary reference values

Hurrell¹,

Egli²

2010

The American Journal of Clinical Nutrition

999

804

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Iron differs from other minerals because iron balance in the human body is regulated by absorption only because there is no physiologic mechanism for excretion. On the basis of intake data and isotope studies, iron bioavailability has been estimated to be in the range of 14-18% for mixed diets and 5-12% for vegetarian diets in subjects with no iron stores, and these values have been used to generate dietary reference values for all population groups. Dietary factors that influence iron absorption, such as phytate, polyphenols, calcium, ascorbic acid, and muscle tissue, have been shown repeatedly to influence iron absorption in single-meal isotope studies, whereas in multimeal studies with a varied diet and multiple inhibitors and enhancers, the effect of single components has been, as expected, more modest. The importance of fortification iron and food additives such as erythorbic acid on iron bioavailability from a mixed diet needs clarification. The influence of vitamin A, carotenoids, and nondigestible carbohydrates on iron absorption and the nature of the "meat factor" remain unresolved. The iron status of the individual and other host factors, such as obesity, play a key role in iron bioavailability, and iron status generally has a greater effect than diet composition. It would therefore be timely to develop a range of iron bioavailability factors based not only on diet composition but also on subject characteristics, such as iron status and prevalence of obesity.Am J Clin Nutr 2010;91(suppl):1461S-7S.

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Body iron excretion by healthy men and women

Cited by 81 publications

References 17 publications

Effect of red beetroot (Beta vulgaris L.) intake on the level of some hematological tests in a group of female volunteers

Effect of red beetroot (Beta vulgaris L.) intake on the level of some hematological tests in a group of female volunteers

Menopause effect on blood Fe and Cu isotope compositions

Iron bioavailability and dietary reference values

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