Body Mass Index and Hospital Discharge Outcomes After Ischemic Stroke

Abstract

Background: Obesity is a risk factor for vascular disease and has been associated with poorer outcomes in hospitalized patients.Objective: To evaluate the relationship between body mass index (BMI) (calculated as weight in kilograms divided by height in meters squared) and discharge outcomes among persons hospitalized for ischemic stroke. Methods:The relationship between BMI and discharge outcomes was analyzed in 805 consecutive patients with ischemic stroke admitted to a university hospital stroke service. Patients were categorized into 4 BMI categories representing lean, overweight, and class I and class II obesity. Outcome measures analyzed included discharge functional activity, direct discharge to home, and length of hospital stay. The independent effect of BMI on outcome was evaluated with regression analysis, adjusting for other variables known to predict outcome after ischemic stroke.

Increased Brain Microvascular MMP-9 and Incidence of Haemorrhagic Transformation in Obese Mice after Experimental Stroke

“…The increased risk of stroke in obese individuals may also be accompanied by poorer prognosis after the ischaemic insult (Razinia et al, 2007). In support of this, recent studies have demonstrated greater brain damage in obese rodents after experimental stroke (Mayanagi et al, 2008;Terao et al, 2008).…”

Obesity

“…A small number of studies suggest that obesity may confer a poorer response to tissue plasminogen activator, 27 lower likelihood of discharge home, 19 and poorer response to rehabilitation. 28 However, the effectiveness of blood pressure lowering therapy after stroke is not affected by body weight.…”

Impact of iterative reconstruction on image quality and radiation dose in multidetector CT of large body size adults

“…Further, a greater percentage increase in skin dose compared with abdominal organ dose is noted as patient size is increased [4]. Limiting dose exposure is of importance as adults with large body habitus generally have an extended hospital stay and a greater number of surgical and medical interventions, making them vulnerable to unwarranted radiation exposure from repeated imaging [8][9][10][11][12]. Moreover, a substantial number of patients with large body habitus are young and often require repeated imaging to study their disease status or to assess the success of various procedures [13,14], further increasing lifetime radiation exposure.…”