Body Mass Index and Outcomes from Pancreatic Resection: a Review and Meta-analysis

Abstract

BMI increases the operative complexity of pancreatectomy. However, with aggressive peri- and post-operative care, increases in BMI-associated morbidity and mortality may be mitigated.

Characteristics of Venous Thromboembolism in Pancreatic Adenocarcinoma in East Asian Ethnics

“…Majumder et al 42 showed positive correlation between obesity and mortality in PC patients in Western but not Asia-Pacific populations. Ramsey and Martin 43 reported that BMI increases the complexity in resection of PC, but aggressive para-operative care could mitigate obesity-associated morbidity and mortality. These two results imply that there is no “universally applicable” relationship between BMI and prognosis in PC and the relationship has to be individually evaluated according to clinical or demographical setting.…”

An analysis of risk factors for pancreatic fistula after robotic pancreaticoduodenectomy: outcomes from a consecutive series of standardized pancreatic reconstructions

“…Median EBL for the (NF) cohort was 250 ml, and MVA confirmed the independent protective effect of minimizing blood loss on the occurrence of POPF post-RPD. Although BMI was not included as a major risk factor in the Braga and Callery scores, obesity is a welldefined risk factor for post-PD complications in general and POPF in particular [38][39][40][41]. Patients with larger BMI harbor more pancreatic steatosis, a finding that may increase the risk of POPF as described by Mathur et al and Gaujax et al [34,35].…”

Obesity and survival in population-based patients with pancreatic cancer in the San Francisco Bay Area

“…The association between obesity and survival from these studies has been mixed [13, 17, 19, 20] and may be explained by a variety of factors including small study size, assessment of outcomes unrelated to obesity, and heterogeneity in criteria for study enrollment and in BMI measures [24]. Additionally, many of these studies were designed to determine how obesity at time of surgery affected patient surgical outcome(s), rather than to assess the relationship between usual adult obesity (or obesity at a specific age) and survival duration in pancreatic cancer patients.…”