Body Mass Index and Stroke Mortality by Smoking and Age at Menopause Among Korean Postmenopausal Women

Yi, Sang-Wook; Odongua, N.; Nam, Chung Mo; Sull, Jae Woong; Ohrr, Heechoul

doi:10.1161/strokeaha.109.555144

Cited by 31 publications

(27 citation statements)

References 27 publications

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“…The association between stroke mortality and overweight has been less studied. Recently, in both Caucasian men and Asian women, overweight was independently associated with a greater risk of stroke death [32,33] . An independent association was also demonstrated between BMI and stroke mortality [3] .…”

Section: Discussionmentioning

confidence: 99%

Socioeconomic and Cardiovascular Variables Explaining Regional Variations in Stroke Mortality in Chile: An Ecological Study

Lavados

Díaz²,

Jadue

et al. 2011

Neuroepidemiology

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Background: Regional differences in stroke mortality rates have been described in Chile. These could be related to the distribution of cardiovascular risk factors, the quality of medical care or socioeconomic status influencing incidence or case fatality rates. Our objective was to investigate variables explaining the variability in stroke mortality rates in the different regions of Chile. Methods: Adjusted stroke mortality rates in different regions were calculated for the year 2003. Variables were added from three sources: the National Death Certificate Database, the National Socioeconomic Characterization Survey and the National Health Survey. A logistic regression model was used to investigate regions, demographic variables and socioeconomic variables associated with the risk of death from stroke. A linear regression model was used to study the association of socioeconomic variables and cardiovascular risk factors with the standardized mortality rate by region and the contribution of these to the variability. Results: A twofold increase was found in adjusted stroke mortality rates among regions. Greater risk was associated with older age, female gender and residence in regions V, VII, VIII and IX. Sixty-two percent of the regional variability rate was explained by the combined prevalence of poverty (34%), diabetes (17%), sedentarism (8%) and overweight (3%). Conclusion: The risk of death from stroke in Chile is associated with age, sex and living in four specific regions of the country. The majority of the increased risk in these regions is explained by the prevalence of poverty, diabetes, a sedentary lifestyle and overweight.

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Section: Discussionmentioning

confidence: 99%

Socioeconomic and Cardiovascular Variables Explaining Regional Variations in Stroke Mortality in Chile: An Ecological Study

Lavados

Díaz²,

Jadue

et al. 2011

Neuroepidemiology

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“…11 In addition, a study among Korean menopausal women revealed an increased risks of total stroke mortality and hemorrhagic stroke mortality with increasing BMI, particularly in those women with early menopause and those who smoked. 12 These discrepancies to the former data may be due to dietary, geographic, or lifestyle differences between Asian and Western populations, 11 whereas gender differences 12 and of course ethnic variances may play also a role.…”

Section: Body Weight and Stroke: Before And After The Eventmentioning

confidence: 96%

Body Weight After Stroke

Scherbakov

Dirnagl

Doehner

2011

Stroke

129

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Background and Purpose-Outcome after acute stroke is determined to a large extent by poststroke complications. Nutritional status and metabolic balance may substantially contribute to outcome after stroke. Key mechanisms of stroke pathophysiology can induce systemic catabolic imbalance with impaired metabolic efficiency and degradation of body tissues. Summary-Tissue wasting, sarcopenia, and cachexia may impair and delay poststroke rehabilitation and worsen the prognosis. Although current guidelines for secondary prevention after stroke recommend weight reduction, increasing evidence suggests that patients who are overweight and mildly obese may actually have a better outcome. An "obesity paradox" has been identified to describe the contrasting impact of being overweight in patients with chronic illness compared with healthy populations. We present an overview on the metabolic regulation in patients with stroke and evaluate current data on the impact of body weight and weight change after stroke. The emerging picture suggests that being overweight and obese may impact patients with stroke differently than it does healthy subjects. Conclusions-We propose that current knowledge on obesity and its management in primary prevention cannot be transferred to patients with established stroke. Systematic studies on changes in body composition after stroke and on treatment options are warranted to establish the pathophysiology and evidence-driven management of nutritional status in these patients. (Stroke. 2011;42:3646-3650.)

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“…Besides the aforementioned statistical concerns, it is unclear if lower BMI was a result of healthy living, medical or psychiatric illness, malnutrition, neglect, lower socioeconomic status, or drug abuse. Of note, two Asian population studies 13,14 did not demonstrate the obesity paradox; the differences in incidence of obesity, lifestyle, and diet may lessen the contribution of corpulence as a risk factor for initial strokes and hence its subsequent "protective" effect. Immobilized limbs after an infarct lose bone mineral density, muscle area, and gain in intramuscular fat with changes possibly accelerating with age.…”

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confidence: 99%