Body mass index and vitamin D level in carpal tunnel syndrome patients

Abstract

BackgroundCarpal tunnel syndrome (CTS) is the most common entrapment neuropathy of the upper extremity. The aim of this study is to evaluate the body mass index (BMI) and vitamin D levels in CTS patients.MethodsThe current study was conducted at Zagazig University Hospitals. It included 50 CTS patients and 50 controls. Clinical assessment was carried out to exclude symptoms and signs of neuropathy. Laboratory investigations including vitamin D levels, glycosylated hemoglobin, liver, and kidney function were carried out for every participant. All patients underwent electrodiagnostic study and completed Boston questionnaire to assess their pain sum score, symptom severity (SSS), and functional status (FSS).ResultsPatients had significantly higher BMI and lower vitamin D levels compared to controls (p = 0.003 and p = 0.001, respectively). Those with severe CTS had a significantly higher BMI and lower vitamin D levels than the others (p = 0.03 and p = 0.01 respectively). No significant difference was found between CTS subgroups regarding the SSS, while a higher significant FSS and pain sum score were reported in the severe CTS patients compared to the other two groups (p = 0.01 and p = 0.04 respectively). A significant negative correlation was detected between vitamin D levels and both of BMI, and Boston pain sum scores (p = 0.01 and p = 0.03 respectively). Also, an inverse correlation was detected between vitamin D levels and both of SSS and FSS (p = 0.14, p = 0.06). Furthermore, a significant positive and negative correlation between vitamin D levels and both of conduction velocity and distal motor latency respectively was observed (p = 0.02 and p = 0.01 respectively).ConclusionsCarpal tunnel syndrome was significantly associated with hypovitaminosis D especially in patients with higher BMI. This highlights the importance of vitamin D supplements and weight loss regimes to minimize the severity of their pain.

Carpel tunnel syndrome: A link with vitamin D and calcium

“…CTS patients had significantly lower vitamin D levels compared with the controls. This observation was in agreement with previously published studies from Tanik et al (4), Nageeb et al (5) and Gürsoy et al (26). In contrast, Lee et al (27) showed there was no difference in vitamin D levels between the patients with CTS and the controls.…”

“…The association between parameters, such as sex, increased age, a high BMI and CTS have been reported in numerous studies. CTS patients have higher BMI values compared with controls (5,43,44), consistent with findings from the present study. Some 45.8% of patients with CTS were obese compared with 18.8% of the controls.…”

“…Several studies have investigated the association between CTS and vitamin D status. The results of these studies suggested that low vitamin D levels are associated with CTS (4)(5)(6). Vitamin D is the most commonly observed single most deficient vitamin in different populations, including in areas of the world that receive sufficient sunlight, such as Jordan (7).…”

Relationship between the severity of carpal tunnel syndrome and lipid profile in patients with tip 2 diabetes mellitus

“…In this study, most cases were mild and moderate in terms of CTS severity. Similar results were also found in many previous studies regarding severity [20][21][22]. We also observed that CTS was more severe among females.…”

Analgesic Drug Use for Carpal Tunnel Syndrome

“…Population at risk for this condition is women and age group of 40 to 60 5 . Some comorbid conditions are also found in CTS, such as obesity, diabetes mellitus, hypothyroid, and pregnancy 6 .…”