Body Mass Index and Waist Circumference Affect Lipid Parameters Negatively in Turkish Women

Özkaya, İsmail; Bavunoğlu, İşıl; Tunçkale, Aydın

doi:10.12691/ajphr-2-6-2

Cited by 13 publications

(10 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…An important observation in these analyses was that HDL-C was negatively correlated to WC, a biomarker of visceral obesity, as well as to BMI. These correlations have been reported by other investigators in heterogeneous populations [ 42 , 43 , 44 , 45 ]. This relationship between WC and HDL-C concentrations can be explained by the changes in fat depots which have an important impact in lipoprotein metabolism [ 46 ].…”

Section: Discussionsupporting

confidence: 89%

Postmenopausal Women Have Higher HDL and Decreased Incidence of Low HDL than Premenopausal Women with Metabolic Syndrome

Fernández

Murillo

2016

Healthcare

View full text Add to dashboard Cite

It is well known that plasma lipids, waist circumference (WC) and blood pressure (BP) increase following menopause. In addition, there is a perceived notion that plasma high-density lipoprotein-cholesterol (HDL-C) concentrations also decrease in postmenopausal women. In this cross-sectional study, we evaluated plasma lipids, fasting glucose, anthropometrics and BP in 88 post and 100 pre-menopausal women diagnosed with metabolic syndrome. No differences were observed in plasma low-density lipoprotein-cholesterol cholesterol, triglycerides, fasting glucose or systolic and diastolic BP between groups. However, plasma HDL-C was higher (p < 0.01) in postmenopausal women and the percentage of women who had low HDL (<50 mg/dL) was higher (p < 0.01) among premenopausal women. In addition, negative correlations were found between WC and HDL-C (r = −0.148, p < 0.05) and BMI and HDL-C (r = −0.258, p < 0.01) for all subjects indicating that increases in weight and abdominal fat have a deleterious effect on plasma HDL-C. Interestingly, there was a positive correlation between age and plasma HDL-C (r = 0.237 p < 0.01). The results from this study suggest that although HDL is decreased by visceral fat and overall weight, low HDL is not a main characteristic of metabolic syndrome in postmenopausal women. Further, HDL appears to increase, not decrease, with age.

show abstract

Section: Discussionsupporting

confidence: 89%

Postmenopausal Women Have Higher HDL and Decreased Incidence of Low HDL than Premenopausal Women with Metabolic Syndrome

Fernández

Murillo

2016

Healthcare

View full text Add to dashboard Cite

show abstract

“…Previous studies support our results and have shown that visceral fat is correlated with metabolic risk factors including a reduction in HDLC as well as an increase in TG and insulin resistance, but not with abdominal subcutaneous fat. 15 16) Many studies have also reported a positive correlation between the TG/HDLC ratio and waist circumference; 17 18 19) however, the correlation between the TG/HDLC ratio and BMI has been inconsistent. 18 19 20) …”

Section: Discussionmentioning

confidence: 99%

The Correlation between the Triglyceride to High Density Lipoprotein Cholesterol Ratio and Computed Tomography-Measured Visceral Fat and Cardiovascular Disease Risk Factors in Local Adult Male Subjects

et al. 2015

View full text Add to dashboard Cite

BackgroundWe studied the association between the triglyceride to high-density lipoprotein cholesterol ratio and computed tomography-measured visceral fat as well as cardiovascular risk factors among Korean male adults.MethodsWe measured triglycerides, high density lipoprotein cholesterol, body mass, waist circumference, fasting plasma glucose, hemoglobin A1c, systolic blood pressure, diastolic blood pressure, visceral fat, and subcutaneous fat among 372 Korean men. The visceral fat and subcutaneous fat areas were measured by computed tomography using a single computed tomography slice at the L4-5 lumbar level. We analyzed the association between the triglyceride to high density lipoprotein cholesterol ratio and visceral fat as well as cardiovascular risk factors.ResultsA positive correlation was found between the triglyceride to high density lipoprotein cholesterol ratio and variables such as body mass index, waist circumference, fasting plasma glucose, hemoglobin A1c, visceral fat, and the visceral-subcutaneous fat ratio. However, there was no significant correlation between the triglyceride to high density lipoprotein cholesterol ratio and subcutaneous fat or blood pressure. Multiple logistic regression analyses revealed significant associations between a triglyceride to high density lipoprotein cholesterol ratio ≥3 and diabetes, a body mass index ≥25 kg/m2, a waist circumference ≥90 cm, and a visceral fat area ≥100 cm2. The triglyceride to high density lipoprotein cholesterol ratio was not significantly associated with hypertension.ConclusionThere were significant associations between the triglyceride to high density lipoprotein cholesterol ratio and body mass, waist circumference, diabetes, and visceral fat among a clinical sample of Korean men. In the clinical setting, the triglyceride to high density lipoprotein cholesterol ratio may be a simple and useful indicator for visceral obesity and cardiovascular disease.

show abstract

“…The same observation was found with TG, LDL, and VLDL, whereas the HDL level was low in both groups with no significant differences. It is known that total cholesterol levels higher than 170 mg/dL and LDL-C levels higher than 110 mg/dL are high risk factors for many diseases [54]. Thus, diet may be responsible for the nonsignificance between the obese and non-obese groups in all lipid parameters.…”

Section: Resultsmentioning

confidence: 99%

Genetic, dietary, and non-dietary risk factors of obesity among preparatory-year female students at Taibah University, Saudi Arabia

Nashar

Alananbeh

Hassan

2017

Journal of Taibah University for Science

View full text Add to dashboard Cite

Genetic factors have a strong influence on obesity and are associated with body mass index (BMI). No study has investigated the relationships between glucose, the fat mass and obesity-associated (FTO) gene, obesity (BMI), and other metabolic-related traits in Saudi Arabia. This study was conducted to identify the association between glucose, BMI and the FTO rs9939609 variant with different metabolic traits among 186 female preparatory students at Taibah University in 2015. The subjects were divided into two categories based on glucose level and BMI. The results showed that 1/10th of the students were non-obese, while approximately 1/3rd had a high glucose level (HGL). The HGL group had higher mean levels of glucose, cholesterol, triglycerides, HDL, LDL, VLDL, and malondialdehyde compared to those of the normal glucose level (NGL) group. A highly positive correlation between glucose and some biochemical parameters was found in the HGL group (P < 0.05), while no correlation was found between glucose and biochemical parameters, except for the cholesterol and triglyceride levels, in the NGL group. According to the t-test, none of the biochemical parameters were significant, and no correlation existed between these parameters and glucose, except for BMI. More than 90% of the students were not aware that they had an HGL or high cholesterol level according to their response to the questionnaire distributed at the beginning of this study. These problems mainly arose from the students' diet, lack of exercise, and lifestyle. Of the 75% of students that had the T-allele, approximately 50% had the heterozygous FTO rs9939609 genotype AT. Genotypes were in Hardy-Weinberg equilibrium (P > 0.05) in the whole population (n = 186) in both obese and non-obese groups and both HGL and NGL groups. In conclusion, a positive correlation between glucose and some biochemical parameters was found in the HGL group; 24.5% of the population had the (A allele) risk factor, and 32% and 98% of the population were homozygous (AA) and heterozygous (AT) for the rs9939609 FTO obesity-risk allele that is responsible for greater energy intake. Future studies are required to study the FTO gene variant and its association with different biochemical parameters, mainly glucose, weight, and BMI, between males and females at different ages and locations in Saudi Arabia.

show abstract

Body Mass Index and Waist Circumference Affect Lipid Parameters Negatively in Turkish Women

Cited by 13 publications

References 26 publications

Postmenopausal Women Have Higher HDL and Decreased Incidence of Low HDL than Premenopausal Women with Metabolic Syndrome

Postmenopausal Women Have Higher HDL and Decreased Incidence of Low HDL than Premenopausal Women with Metabolic Syndrome

The Correlation between the Triglyceride to High Density Lipoprotein Cholesterol Ratio and Computed Tomography-Measured Visceral Fat and Cardiovascular Disease Risk Factors in Local Adult Male Subjects

Genetic, dietary, and non-dietary risk factors of obesity among preparatory-year female students at Taibah University, Saudi Arabia

Contact Info

Product

Resources

About