Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study

Peralta, Gabriela P.; Marcon, Alessandro; Carsin, Anne-Elie; Abramson, Michael J.; Accordini, Simone; Amaral, André F.S.; Antó, Josep M.; Bowatte, Gayan; Burney, Peter; Corsico, Angelo Guido; Demoly, Pascal; Dharmage, Shyamali C.; Forsberg, Bertil; Fuertes, Elaine; García-Larsen, Vanessa; Gíslason, Þórarinn; Blanco, José Antonio Gullón; Heinrich, Joachim; Holm, Mathias; Jarvis, Déborah; Janson, Christer; Jõgi, Rain; Johannessen, Ane; Leynaert, Bénédicte; Rovira, Jesús Martínez Moratalla; Nowak, Dennis; Probst‐Hensch, Nicole; Rahérison, Chantal; Sánchez-Ramos, José Luis; Sigsgaard, Torben; Siroux, Valérie; Squillacioti, Giulia; Urrutia, Isabel; Weyler, Joost; Zock, Jan Paul; Garcia‐Aymerich, Judith

doi:10.1136/thoraxjnl-2019-213880

Cited by 61 publications

(52 citation statements)

References 32 publications

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“…The test revealed the data significantly follows normal distribution (p>0.05). Therefore, a parametric test Two-way MANOVA was carried out to see the effect of age groups (18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30), gender (male, female) on parameters. Also, the interaction effect of age*gender is observed.…”

Section: Resultsmentioning

confidence: 99%

“…However, it was noticed that there was a subsequent decline in forced expiratory volume and Forced Vital Capacity in the age group of 25 to 30 years as compared to the younger age group of 18 to 24 years, and this could be due to the decline in function that rapidly accelerates with age, as documented by [23] which is due to a relatively larger lung, that takes longer time to empty, also there was a decline in pulmonary recoil with advancing years. The findings established age plays an important role in determining the significance of pulmonary function which are related to the physiological changes that take place across one's span of life [24] Fig 7:-Shows the effect of age Group II (25-30 years) with respect to Body Mass Index Fig. 7.…”

Section: Parameters Of Pulmonary Function (N=30)mentioning

confidence: 99%

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Pulmonary Function Test of Forced Vital Capacity and Slow Vital Capacity Using Spirometry in Young Adults With Respect to Body Mass Index: A Normative Study

Anthraper¹,

Roy²

2020

IJISRT

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Objectives: To determine the effect of Age, Gender and its correlation on pulmonary functions of Forced Vital Capacity and Slow Vital Capacity in Group I (18-24 years) and Group II (25-30 years) with respect to Body Mass Index.  Methodology: Sixty healthy adults between 18-30 years were included in the study. Participants were subdivided into Group I (18 to 24 years) and Group II (25 to 30 years) each group having 15 males and 15 females. The parameters considered were expiratory reserve volume, tidal volume, inspiratory capacity, forced vital capacity and slow vital capacity. Spirometer RMS HELIOS 401 was used. Procedures were explained to each participant; best values from 3 maneuvers were documented and were subjected to analysis.  Results: It is noticed a significant difference in various parameters of pulmonary function. As age increases there was an increase in body mass index and the lung volume also increased. Overall males had higher pulmonary function compared to females, males in Group II (25-30 years) was better compared to males in Group I (18-24 years). With an increase in body mass index, pulmonary function was increased in males compared to females. Age, gender, age, and gender interaction effect with respect to Body Mass Index was seen.  Conclusion: Values obtained can be used as reference standard for estimation of lung volume for age group 18-30 years. In future, Spirometry can be used as a clinical assessment and management tool in the field of speech language pathology, by modifying respiratory patterns to control lung volumes, phonations and the flow of speech.

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Section: Resultsmentioning

confidence: 99%

Section: Parameters Of Pulmonary Function (N=30)mentioning

confidence: 99%

Pulmonary Function Test of Forced Vital Capacity and Slow Vital Capacity Using Spirometry in Young Adults With Respect to Body Mass Index: A Normative Study

Anthraper¹,

Roy²

2020

IJISRT

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“…Крім надзвичайно поширених ускладнень з боку серцево-судинної системи [4,5,6], при ожирінні визначаються й інші патологічні стани, зокрема -патологія дихальної системи (ДС), яка представлена синдромом обструктивного апное сну, гіповентиляційним синдромом, гіперреактивністю бронхів, пневмонією, легеневою гіпертензією [7,8,9].…”

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“…Порушення зовнішнього дихання при абдомінальному ожирінні (АО) виникають навіть при відсутності бронхолегеневих захворювань, а при їх наявності воно обтяжує прогноз [9,10,11]. Чинники, що негативно впливають на функцію зовнішнього дихання при ожирінні та змінюють патерн дихання, можна систематизувати як механічні фактори (зменшення легеневих обсягів, звуження дистальних дихальних шляхів) та як порушення фізіологічного газообміну [11,12].…”

unclassified

“…В результаті значно порушується легенева вентиляція, зменшуються легеневі об'єми (особливо резервний обсяг видиху і функціональна резервна ємність), які відіграють чільну роль у підтримці прохідності дистальних дихальних шляхів. Зниження резервного об'єму видиху нижче об'єму закриття призводить до колапсу бронхіол і формуванню мікроателектазів [9,12,14].…”

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Effectiveness of Physical Therapy in the Correction of Respiratory System Dysfunction Signs in Women with Abdominal Obesity

Аравіцька¹

2020

Ukr. ž. med. bìol. sportu

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Respiratory disorders in obesity occur even in the absence of bronchopulmonary pathology, and in their presence, an excess of adipose tissue worsens the prognosis of the disease. Obese people have a high risk of obstructive sleep apnea syndrome, hypoventilation syndrome, bronchial hyperreactivity, pneumonia, pulmonary hypertension. The purpose of the study was to determine the effectiveness of using physical therapy in the correction of signs of respiratory system dysfunction in women with abdominal obesity. Material and methods. The study involved 172 women with abdominal obesity of I-III degrees, diagnosed by body mass index and the ratio of waist and hip circumferences. According to the results of the definition of the rehabilitation (therapeutic) alliance, they were divided into two groups. The comparison group consisted of women with a low level of alliance that refused to actively participate in the program of weight loss. The main group consisted of women with a high level of alliance; they underwent a one-year correction program using nutritional modification, increased physical activity, lymphatic drainage, psychocorrection, and elements of respiratory physical therapy. The control group consisted of 32 women with normal body weight. Subjective state, dyspnea intensity, pulsоoximetry and spirometry parameters were studied. Results and discussion. We revealed the respiratory system dysfunction in women with abdominal obesity: subjective signs of impaired respiratory function, a decrease in arterial blood oxygenation, and a decrease in spirometry volumes. Their content and severity were proportional to the severity of obesity. Using respiratory therapy elements in the program of complex physical therapy aimed at reducing body weight let us normalize the studied parameters of the respiratory system function in women of the main group. The low level of the rehabilitation alliance of women in the comparison group led to unsatisfactory implementation of the recommendations provided and was associated with a lack of rehabilitation effect. Improvement in the state of the bronchopulmonary system in women with abdominal obesity is justified both by primary changes in the respiratory system – an increase in spirometry volumes and reserves, improved blood oxygenation, and indirectly – by an increase in the range of motion of the diaphragm, a decrease in the amount of visceral fat and general fitness, which is confirmed by the leveling of signs of restrictive and mixed respiratory failure. Conclusion. It is advisable to include the elements of respiratory rehabilitation in the programs for restoring the health of women with abdominal obesity

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Relationships between lung function decline and skeletal muscle and fat mass changes: a longitudinal study in healthy individuals

Park

Lee

et al. 2021

J cachexia sarcopenia muscle

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BackgroundThe associations between long-term changes in body mass composition and decline in lung function in healthy adults are unknown. Methods Using a well-defined health check-up database, we first assessed individual longitudinal changes in muscle mass (MM) and fat mass (FM) measured via bioelectrical impedance analyses. Then we classified the enrolled individuals into five body composition groups according to their MM index (MMI) [MM (kg)/height (m) 2 ] or FM index (FMI) [FM (kg)/height (m) 2 ] change rate quartiles. Linear mixed models adjusted for age, smoking status, height, and body mass index were used to analyse the rate of forced expiratory volume in 1 s (FEV1) decline and body composition groups. Results A total of 15 476 middle-aged individuals (6088 women [mean age ± standard deviation: 50.74 ± 7.44] and 9388 men [mean age ± standard deviation: 49.36 ± 6.99]) were enrolled. The mean number of measurements was 6.96 (interquartile range [IQR]: 5-9) over an average follow-up period of 8.95 years (IQR: 6.73-11.10). Decrease in MMI was significantly associated with accelerated FEV1 decline in men only (P = 1.7 × 10 À9 ), while increase in FMI was significantly associated with accelerated FEV1 decline in both women and men (P = 7.9 × 10 À10 and P < 2.0 × 10 À16 respectively). Linear mixed model analyses indicated that annual increase of 0.1 kg/m 2 in MMI was related to accelerated FEV1 decline by 30.79 mL/year (95% confidence interval [CI]: 26.10 to 35.48 mL/year) in men. Annual increase of 0.1 kg/m 2 in FMI was related to accelerated FEV1 decline by 59.65 mL/year in men (95% CI: 56.84 to 62.28 mL/year) and by 22.84 mL/year in women (95% CI: 18.95 to 26.74 mL/year). In body composition analysis, we found increase in MMI was significantly associated with attenuated FEV1 decline in men only (P = 1.7 × 10 À9 ), while increase in FMI was significantly associated with accelerated FEV1 decline in both women and men (P = 7.9 × 10 À10 and P < 2.0 × 10 À16 respectively). Individuals characterized with gain MM combined with loss of FM were associated with the most favourable outcome (i.e. the smallest rate of decline in FEV1) in both women and men. In men, loss of FM over time is more closely related with attenuated FEV1 decline than change in MM (gain or loss). Conclusions Change in body composition over time can be used to identify healthy middle-aged individuals at high risk for rapid FEV1 decline.

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Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study

Cited by 61 publications

References 32 publications

Pulmonary Function Test of Forced Vital Capacity and Slow Vital Capacity Using Spirometry in Young Adults With Respect to Body Mass Index: A Normative Study

Pulmonary Function Test of Forced Vital Capacity and Slow Vital Capacity Using Spirometry in Young Adults With Respect to Body Mass Index: A Normative Study

Effectiveness of Physical Therapy in the Correction of Respiratory System Dysfunction Signs in Women with Abdominal Obesity

Relationships between lung function decline and skeletal muscle and fat mass changes: a longitudinal study in healthy individuals

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