Body mass index, respiratory conditions, asthma, and chronic obstructive pulmonary disease

Abstract

Background This study aims to assess the relationship of body mass index (BMI) status with respiratory conditions, asthma, and chronic obstructive pulmonary disease (COPD) in a state population. Methods Self-reported data from 11,868 adults aged ≥18 years in the 2012 South Carolina Behavioral Risk Factor Surveillance System telephone survey were analyzed using multivariable logistic regression that accounted for the complex sampling design and adjusted for sex, age, race/ethnicity, education, smoking status, physical inactivity, and cancer history. Results The distribution of BMI (kg/m2) was 1.5% for underweight (<18.5), 32.3% for normal weight (18.5-24.9), 34.6% for overweight (25.0-29.9), 26.5% for obese (30.0-39.9), and 5.1% for morbidly obese (≥40.0). Among respondents, 10.0% had frequent productive cough, 4.3% had frequent shortness of breath (SOB), 7.3% strongly agreed that SOB affected physical activity, 8.4% had current asthma, and 7.4% had COPD. Adults at extremes of body weight were more likely to report having asthma or COPD, and to report respiratory conditions. Age-adjusted U-shaped relationships of BMI categories with current asthma and strongly agreeing that SOB affected physical activity, but not U-shaped relationship with COPD, persisted after controlling for the covariates (p<0.001). Morbidly obese but not underweight or obese respondents were significantly more likely to have frequent productive cough and frequent SOB than normal weight adults after adjustment. Conclusion Our data confirm that both underweight and obesity are associated with current asthma and obesity with COPD. Increased emphasis on exercise and nutrition may improve respiratory conditions.

Association of systemic inflammation, adiposity, and metabolic dysregulation with asthma burden among Hispanic adults

“…Although our findings for general adiposity and symptoms extend those of prior studies [48–50] to U.S. Hispanics, we did not replicate a linear association between BMI and asthma symptoms found in non-Hispanic whites [49]. Further, attenuation of the association of abnormal waist circumference with FVC and FEV 1 , when adjusted for hs-CRP and HDL, suggest that systemic inflammation and metabolic dysregulation, intricately linked to truncal adiposity, drive its association with asthma burden.…”

Associations of body condition score with health conditions related to overweight and obesity in cats

“…, Liu et al . ). Several mechanisms have been proposed for this association, including a reduction in lung volume, secretion of inflammatory mediators and an increase in gastro‐oesophageal reflux (Eneli et al .…”

The impact of overweight and obesity on acute exacerbations of COPD - subgroup analysis of the Taiwan obstructive lung disease cohort

“…Some studies have reported that overweight or obesity had a protective effect against mortality in patients with COPD, 6,7,9 while others have reported a worse HRQL, increased severity of dyspnea and frequency of severe exacerbations in obese patients with COPD. [10][11][12] To the best of our knowledge, few studies have explored the relationship between overweight or obesity and the frequency of COPD exacerbations. [12][13][14][15] Therefore, the aim of this study was to examine whether overweight and obesity are associated with the frequency of acute exacerbations in patients with COPD in Taiwan.…”