Body Protein Index Based on Bioelectrical Impedance Analysis Is a Useful New Marker Assessing Nutritional Status: Applications to Patients with Chronic Renal Failure on Maintenance Dialysis

Nakao, Toshiyuki; Kanazawa, Yuki; Nagaoka, Yume; Iwasawa, Hideaki; Uchinaga, Asako; Matsumoto, Hiroshi; Okada, Tomonari; Yoshino, Maki

doi:10.1159/000100993

Cited by 26 publications

(17 citation statements)

References 21 publications

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“…The finding is not new, yet its effects have not been fully established (25). Interestingly, BPI was significantly lower in this study population than in a comparable Japanese HD population, possibly due to ethnic differences (29). Establishing such differences before testing BPI as a marker of nutritional status seems necessary.…”

Section: Discussionmentioning

confidence: 72%

Nutritional Status Evaluated by Multi‐Frequency Bioimpedance Is Not Associated With Quality of Life or Depressive Symptoms in Hemodialysis Patients

et al. 2010

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Hemodialysis therapy significantly impacts on patients' physical, psychological, and social performances. Such reduced quality of life depends on several factors, such as malnutrition, depression, and metabolic derangements. This study aims to evaluate the current nutritional status, quality of life and depressive symptoms, and determine the possible relationships with other risk factors for poor outcomes, in stable hemodialysis patients. This was a single-center, cross-sectional study that enrolled 59 adult patients undergoing hemodialysis. Laboratory tests that included high-sensitivity c-reactive protein (CRP), and quality of life and depressive symptom evaluation, as well as malnutrition-inflammation score, nutritional status and body composition (by direct segmental multi-frequency bioimpedance analysis) determinations were performed. Patients were classified as "underfat", "standard", "overfat", or "obese" by multi-frequency bioimpedance analysis. Seven patients were underfat, 19 standard, 19 overfat, and 14 obese. Triglyceride levels significantly differed between the underfat, standard, overfat, and obese groups (1.06 [0.98-1.98]; 1.47 [1.16-1.67]; 2.53 [1.17-3.13]; 2.12 [1.41-2.95] mmol/L, respectively; P=0.026), as did Kt/V between the underfat, overfat, and obese groups (1.49 ± 0.14; 1.23 ± 0.19; 1.19 ± 0.22; P=0.015 and P=0.006, respectively). Depressive symptoms, quality of life, and CRP and phosphate levels did not diverge among nutritional groups. Creatinine, albumin, and phosphate strongly correlated, as well as percent body fat, body mass index, and waist circumference (r=0.859 [P<0.001], and r=0.716 [P<0.001], respectively). Depressive symptoms and physical and psychological quality-of-life domains also strongly correlated (r(s) = -0.501 [P<0.001], r(s) = -0.597 [P<0.001], respectively). The majority of patients were overfat or obese and very few underfat. Inflammation was prevalent, overall. No association of nutritional status with malnutrition-inflammation, quality of life, or depressive symptoms could be established.

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Section: Discussionmentioning

confidence: 72%

Nutritional Status Evaluated by Multi‐Frequency Bioimpedance Is Not Associated With Quality of Life or Depressive Symptoms in Hemodialysis Patients

et al. 2010

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“…Instead, BIA has been reported to be a useful tool to measure body composition including muscle mass, fat mass and water volume because of its noninvasiveness, availability and simplicity. Recent developments regarding the precision of BIA devices and determination of the appropriate timing to estimate body composition in HD patients have enabled accurate measurement of the body composition in HD patients by BIA methods . Di Lorio et al.…”

Section: Discussionmentioning

confidence: 99%

Skeletal Muscle Loss Is Negatively Associated With Single‐Pool Kt/V and Dialysis Duration in Hemodialysis Patients

et al. 2014

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We evaluated the skeletal muscle loss in hemodialysis (HD) patients by bioelectrical impedance analysis (BIA) and handgrip strength test. Thirty-four HD patients and 16 healthy subjects (control group) were measured for skeletal muscle mass normalized as the skeletal muscle mass index (SMI), calculated as skeletal muscle mass (kg)/height (m)(2) using a tetrapolar bioelectrical impedance plethysmograph. Handgrip strength test was also performed using a hand dynamometer in both groups. In HD patients, the associations of SMI and handgrip strength with age, sex, HD conditions, and HD parameters such as body mass index (BMI), single-pool Kt/V (spKt/V), normalized protein catabolic rate (nPCR), creatinine generation rate (CGR) and serum albumin level (Alb) were investigated. SMI of HD patients (4.58 ± 0.95 kg/m(2) ) was significantly lower than that of the control group (5.55 ± 0.80 kg/m(2) , P<0.01). The handgrip strength of HD patients (19.9 ± 7.74 kg) was also significantly lower than that of the control group (33.0 ± 8.94 kg, P<0.01). In HD patients, HD duration was associated with both SMI and handgrip strength. Among HD parameters, spKt/V was negatively associated with both SMI and handgrip strength, BMI and Alb were positively associated with SMI, while nPCR and CGR were associated with neither SMI nor handgrip strength. HD duration independently contributed to skeletal muscle loss and the value of spKt/V may be affected by skeletal muscle loss in HD patients.

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“…One of its most studied utilizations is in patients on dialysis [38,39,40 ], especially because of the difficulty to perform anthropometric and laboratorial nutritional assessment of such patients. In their study of the prevalence of undernutrition in children on peritoneal dialysis, Edefonti et al [41] demonstrated that the electrical bioimpedance was more sensitive to body changes than the anthropometric measurements.…”

Section: Laboratory Assessment Of Body Compositionmentioning

confidence: 99%

Challenges of nutritional assessment in pediatric ICU

Feferbaum¹,

Delgado²,

Zamberlan

et al. 2009

Current Opinion in Clinical Nutrition and Metabolic Care

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Nutritional assessment is one of the main aspects of the pediatric intensive care patient and is the most important tool to avoid hospital undernutrition. There is currently no gold standard for nutritional assessment in the pediatric ICU. The results of anthropometric and laboratory markers must be jointly analyzed, but individually interpreted according to disease and metabolic changes, in order to reach a correct diagnosis of the nutritional status and to plan and monitor the nutritional treatment.

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Body Protein Index Based on Bioelectrical Impedance Analysis Is a Useful New Marker Assessing Nutritional Status: Applications to Patients with Chronic Renal Failure on Maintenance Dialysis

Cited by 26 publications

References 21 publications

Nutritional Status Evaluated by Multi‐Frequency Bioimpedance Is Not Associated With Quality of Life or Depressive Symptoms in Hemodialysis Patients

Nutritional Status Evaluated by Multi‐Frequency Bioimpedance Is Not Associated With Quality of Life or Depressive Symptoms in Hemodialysis Patients

Skeletal Muscle Loss Is Negatively Associated With Single‐Pool Kt/V and Dialysis Duration in Hemodialysis Patients

Challenges of nutritional assessment in pediatric ICU

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