Body weight adapted tinzaparin treatment in patients with obesity

Weight-adjusted dosing of tinzaparin for thromboprophylaxis in obese medical patients

“…A recent case series examined obese medical patients receiving 175 IU/kg tinzaparin per actual bodyweight. Only 13.3% of them had anti-Xa activities below the target range and no overdosing occurred up to a bodyweight of 222 kg [ 20 ]. However, there are very few studies focusing on thromboprophylaxis with tinzaparin in obese patients and most of them have been carried out in patients undergoing bariatric surgery, [ [21] , [22] , [23] ] whereas there are no published reports on thromboprophylaxis with tinzaparin in obese medical patients.…”