Bombesin inhibits growth hormone response to insulin-induced hypoglycemia in humans

Growth Hormone Neuroregulation and Its Alterations in Disease States

“…Both galanin and aMSH increase plasma GH levels in normal subjects (Strauchi, 1973;Bauer et al, 1986). Bombesin reduces GH responses to insulin-induced hypoglycaemia without affecting basal GH levels in normal subjects (Scarpignato et al, 1986). Other peptides such as secretin, calcitonin, PHI, CCK (McCann, 1982) CRF and delta sleep-inducing peptide (Iyer & McCann, 1987) modify GH secretion in some experimental animal models but their physiological roIe remains unknown.…”