Bond strength of demineralized dentin after synthesized collagen/hydroxyapatite nanocomposite application

Abdelshafi, Mostafa A.; Fathy, Salma M.; Elkhooly, Tarek A.; Reicha, Fikry M.; Osman, Manal F.

doi:10.1016/j.jmbbm.2021.104590

Cited by 10 publications

(6 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sharifi et al prepared HP–gelatin/curcumin nanocomposites and evaluated their antimicrobial effects against Escherichia coli, Staphylococcus aureus , and Streptococcus mutans [ 66 ]. There are various reports where the group has used different natural polymers for changing the properties of the organic component of the nanocomposites [ 67 ]. Consecutively, other scientific groups presented HA nanocomposites coupled with the antimicrobial effect of metallic NPs such as silver (Ag), gold, iron, silica, and Zn (Zn).…”

Section: Application Of the Nano Dentistrymentioning

confidence: 99%

Nanomaterials in Dentistry: Current Applications and Future Scope

et al. 2022

View full text Add to dashboard Cite

Nanotechnology utilizes the mechanics to control the size and morphology of the particles in the required nano range for accomplishing the intended purposes. There was a time when it was predominantly applied only to the fields of matter physics or chemical engineering, but with time, biological scientists recognized its vast benefits and explored the advantages in their respective fields. This extension of nanotechnology in the field of dentistry is termed ‘Nanodentistry.’ It is revolutionizing every aspect of dentistry. It consists of therapeutic and diagnostic tools and supportive aids to maintain oral hygiene with the help of nanomaterials. Research in nanodentistry is evolving holistically but slowly with the advanced finding of symbiotic use of novel polymers, natural polymers, metals, minerals, and drugs. These materials, in association with nanotechnology, further assist in exploring the usage of nano dental adducts in prosthodontic, regeneration, orthodontic, etc. Moreover, drug release cargo abilities of the nano dental adduct provide an extra edge to dentistry over their conventional counterparts. Nano dentistry has expanded to every single branch of dentistry. In the present review, we will present a holistic view of the recent advances in the field of nanodentistry. The later part of the review compiled the ethical and regulatory challenges in the commercialization of the nanodentistry. This review tracks the advancement in nano dentistry in different but important domains of dentistry.

show abstract

Section: Application Of the Nano Dentistrymentioning

confidence: 99%

Nanomaterials in Dentistry: Current Applications and Future Scope

et al. 2022

View full text Add to dashboard Cite

show abstract

“…A total of 216 studies were not included; many studies were excluded based on the eligibility criteria (182); data not available ( Mazzoni et al, 2013b ); without long-term bond strength ( Hass et al, 2016a ), and conducted on bovine teeth ( Comba et al, 2020 ). Finally, seven-eight studies were included in the review ( Cova et al, 2011 ; Castellan et al, 2013 ; Chiang et al, 2013 ; Andre et al, 2015 ; Carvalho et al, 2016 ; Abunawareg et al, 2017 ; Bacelar-Sa et al, 2017 ; Albuquerque et al, 2019 ; Costa et al, 2019 ; Czech et al, 2019 ; Baena et al, 2020 ; Beck and Ilie, 2020 ; Comba et al, 2020 ; Abdelshafi et al, 2021 ; Baldion et al, 2021 ; Chen et al, 2021 ; Dacoreggio et al, 2021 ; Abd El-Aal et al, 2022 ; Beck and Ilie, 2022 ) and meta-analysis for which the primary data (mean bond strength, standard deviation, and the number of test samples) could be retrieved.…”

Section: Resultsmentioning

confidence: 99%

Effect of collagen cross-linkers on dentin bond strength: A systematic review and network meta-analysis

Chen

Sun

Wang

et al. 2023

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

Objective: This study aimed to evaluate the role of collagen cross-linkers in the bonding performance of the resin-dentin interface through a systematic review and a network meta-analysis.Sources: The literature search was conducted in several databases like PubMed, EMBASE, Cochrane, Scopus and Web of Science from their inception till 30 April 2022.Study selection: The inclusion criteria consisted of in vitro studies evaluating the micro-tensile and micro-shear bond strengths of different cross-linkers acting on dentin. Bayesian network meta-analysis was conducted using RStudio.Data: Out of the 294 studies evaluated in the full-text analysis, 40 were included in the systematic review and meta-analysis. Most studies have used cross-linkers as primer (65.1%), followed by incorporating them into in adhesives and acid etching agents. The application methods of the adhesive system were classified as “etch-and-rinse (ER) adhesives” (77%) and “self-etching (SE) adhesives”. Moreover, there were six types of cross-linkers in this presented review, of which the most numerous were polyphenols.Conclusion: Different application methods of cross-linkers, the long-term results showed that were only effective when used for longer durations, the immediate results were not statistically different. According to immediate and long-term results, etch-and-rinse (ER) adhesives showed a greater bonding performance than the control groups (p ≤ 0.05), whereas self-etching (SE) adhesives showed similar bond strength values (p ≥ 0.05). The result of network meta-analysis (NMA) showed that Dope like compound showed higher long-term bonding performance than other cross-linkers.Clinical significance: Long-term clinical studies may be needed to determine the effect of the cross-linkers on the bonding properties.

show abstract

“…The concentrations of the primers investigated in this study were based on previous studies; 16 , 17 , 25 these primers almost had no cytotoxic effects on cells, and could promote collagen cross-linking. Based on the observation of the color of dentin treated with the four polyphenols, only PA caused a significantly darker staining, which is contrary to the concept of esthetic restoration.…”

Section: Discussionmentioning

confidence: 99%

“…In this stage, 55 mg/mL PA/ethanol, 0.2 mg/mL myricetin/ethanol, 10 mg/mL resveratrol/ethanol, and 10 mg/mL kaempferol/ethanol primers were prepared and stored at 4°C before use. 16 , 17 , 25 , 27 All the chemical reagents were purchased from Macklin, Shanghai, China. Dentin slices were immersed in 1 M/L hydrochloric acid (HCl) for 12 h for complete demineralization (examined using an intraoral dental X-ray device [Focus 50540-IMG, KAVO, California, USA]), 28 rinsed completely with double distilled water, and blotted dry.…”

Section: Methodsmentioning

confidence: 99%

“…[19][20][21][22] PA has been shown to have positive effects on dentin remineralization. [23][24][25] In the past 3 years, the clinical value of myricetin, resveratrol, and kaempferol has gradually increased, and these polyphenols have been proven to improve the resin-dentin bonding durability by modifying collagen and inhibiting MMP activity; [16][17][18] however, their contribution to biomimetic remineralization remains unclear.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Polyphenols Can Improve Resin-Dentin Bond Durability by Promoting Amorphous Calcium Phosphate Nanoparticles to Backfill the Dentin Matrix

Wang¹,

Han²,

You³

et al. 2023

IJN

View full text Add to dashboard Cite

Objective To investigate the effects of proanthocyanidins (PA), myricetin, resveratrol, and kaempferol on the modification of dentin collagen and the inhibition of matrix metalloproteinase (MMP) activity, and to evaluate their contributions to the biomimetic remineralization and resin-dentin bonding performance. Methods Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) and in situ zymography were applied to verify the collagen modification and MMP activity inhibition induced by these four polyphenols. Scanning electron microscopy/energy dispersive spectrometer (SEM/EDS) analysis, X-ray diffraction (XRD), ATR-FTIR, Vickers hardness numbers (VHN), and micro-computed tomography (micro-CT) were performed to characterize the remineralized dentin. Microtensile bond strength (μTBS) and nanoleakage were investigated to evaluate the effects of the four polyphenols on resin-dentin bonding durability. Results ATR-FTIR and in situ zymography confirmed that these four polyphenols could modify dentin collagen and inhibit MMP activity, respectively. Chemoanalytic characterization exhibited the efficacies of the four polyphenols in promoting dentin biomimetic remineralization. The surface hardness of PA-pretreated dentin was the greatest. Micro-CT results demonstrated that the PAs group possessed the highest amount of dentin surface minerals and the lowest amount of deep-layer minerals. The surface and deep-layer mineral contents of the Myr group were higher than Res and Kae groups. Treatment with these four polyphenols significantly increased the initial μTBS compared with the control group without primer conditioning. μTBS decreased significantly during aging, and the decrease was more severe in the PAs and Kae groups than in the Myr and Res groups. With or without aging, the polyphenol groups exhibited relatively less fluorescence. However, the Myr and Res groups showed less serious nanoleakage after aging. Conclusion PA, myricetin, resveratrol, and kaempferol can modify dentin collagen, inhibit MMP activity, promote biomimetic remineralization, and improve resin-dentin bond durability. Compared with PA and kaempferol, myricetin and resveratrol are more effective in improving resin-dentin bonding.

show abstract

Bond strength of demineralized dentin after synthesized collagen/hydroxyapatite nanocomposite application

Cited by 10 publications

References 32 publications

Nanomaterials in Dentistry: Current Applications and Future Scope

Nanomaterials in Dentistry: Current Applications and Future Scope

Effect of collagen cross-linkers on dentin bond strength: A systematic review and network meta-analysis

Polyphenols Can Improve Resin-Dentin Bond Durability by Promoting Amorphous Calcium Phosphate Nanoparticles to Backfill the Dentin Matrix

Contact Info

Product

Resources

About