Bone age in children of diverse ethnicity.

Ontell, Francesca K.; Ivanović, Marija; Ablin, Deborah S.; Barlow, Ted W.

doi:10.2214/ajr.167.6.8956565

Cited by 190 publications

(131 citation statements)

References 3 publications

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“…It is well known that different populations have a different tempo of maturation, so it is not to be expected that the average GP BA of children of different populations agrees with their CA [4,5]. Instead, BA assessment should be regarded as a quantification of the aspects of bone morphology that are related to maturation.…”

Section: Introductionmentioning

confidence: 99%

Automatic determination of Greulich and Pyle bone age in healthy Dutch children

Rijn

Lequin

Thodberg³

2009

Pediatr Radiol

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Background Bone age (BA) assessment is a routine procedure in paediatric radiology, for which the Greulich and Pyle (GP) atlas is mostly used. There is rater variability, but the advent of automatic BA determination eliminates this. Objective To validate the BoneXpert method for automatic determination of skeletal maturity of healthy children against manual GP BA ratings. Materials and methods Two observers determined GP BA with knowledge of the chronological age (CA). A total of 226 boys with a BA of 3-17 years and 179 girls with a BA of 3-15 years were included in the study. BoneXpert's estimate of GP BA was calibrated to agree on average with the manual ratings based on several studies, including the present study. Results Seven subjects showed a deviation between manual and automatic BA in excess of 1.9 years. They were rerated blindly by two raters. After correcting these seven ratings, the root mean square error between manual and automatic rating in the 405 subjects was 0.71 years (range 0.66-0.76 years, 95% CI). BoneXpert's GP BA is on average 0.28 and 0.20 years behind the CA for boys and girls, respectively. Conclusion BoneXpert is a robust method for automatic determination of BA.

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Section: Introductionmentioning

confidence: 99%

Automatic determination of Greulich and Pyle bone age in healthy Dutch children

Rijn

Lequin

Thodberg³

2009

Pediatr Radiol

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“…In 1975, Roche et al (4) showed that the average child in the United States was less physically mature than the children in the Greulich and Pyle atlas. In 1996, Ontell et al (5) examined the applicability of the Greulich and Pyle standards to ethnically diverse children. However, these studies and various others (6)(7)(8) did not provide a large-scale systematic method for validation.…”

mentioning

confidence: 99%

Racial Differences in Growth Patterns of Children Assessed on the Basis of Bone Age

Zhang

Sayre²,

Vachon³

et al. 2009

Radiology

151

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“…To determine whether the G&P standard can still be applied to American children of diverse ethnicity in 1996, Ontell et al (8) found that bone maturity in Asian and Caucasian American girls approximated chronologic age throughout childhood (Table 1). The only significant discrepancy that they found was in Caucasian adolescent girls, whose bone maturity exceeded their chronologic age by w4 months (8).…”

Section: Introductionmentioning

confidence: 99%

DIAGNOSIS OF ENDOCRINE DISEASE: On the need for national-, racial-, or ethnic-specific standards for the assessment of bone maturation

Hochberg

2016

European Journal of Endocrinology

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In an attempt to overcome ethnic and racial differences in skeletal maturation, the use of ethnic-specific standards has been suggested. Do we need such standards? Based on a fundamental understanding of phenotypic plasticity and an individual's ability to respond to environmental cues, the author argues that we do not need ethnic-specific standards for bone maturity. I suggest that we use a unified international standard of bone maturity for comparing the health, nutrition, and quality of life of all children, regardless of their race, nationality, and ethnicity.

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Bone age in children of diverse ethnicity.

Cited by 190 publications

References 3 publications

Automatic determination of Greulich and Pyle bone age in healthy Dutch children

Automatic determination of Greulich and Pyle bone age in healthy Dutch children

Racial Differences in Growth Patterns of Children Assessed on the Basis of Bone Age

DIAGNOSIS OF ENDOCRINE DISEASE: On the need for national-, racial-, or ethnic-specific standards for the assessment of bone maturation

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