Bone allograft provides bone healing in the medial opening high tibial osteotomy

Abstract

Various materials are used to fill osteotomy defects created in the medial opening wedge high tibial osteotomy (MOWHTO). Our hypothesis was that a bone allograft would provide the osteotomy site bone healing within the expected time. We performed the MOWHTO using a cancellous bone allograft in 310 knees in 284 patients between 2000 and 2005.Internal fixation was achieved with a T-profile AO plate. Preoperative and postoperative radiographic measurements were taken and statistically processed. All patients were followed up for a period ranging from three to eight years, or 5.9 years on average. Implanted cancellous bone allografts ≤9 mm healed within 12 weeks in 90% of cases. With the properly selected patient and surgical technique, use of a cancellous bone allograft in MOWHTO represents a satisfactory choice in providing bone healing.

Bovine xenograft locking Puddu plate versus tricalcium phosphate spacer non-locking Puddu plate in opening-wedge high tibial osteotomy: a prospective double-cohort study

“…Several authors have reported good results with allograft [3][4][5], despite the fact that it is associated with a higher failure rate when compared to autograft [16]. The augmentation with calcium phosphate ceramics has been also investigated [12,13], while the experience with xenograft is scanty [6].…”

“…Several strategies have been proposed as alternatives to autologous bone graft, including allograft [3][4][5], xenograft [6], hydroxyapatite [7][8][9], acrylic cement [10,11] and calcium phosphate [12,13] wedges.…”

Hemi-wedge osteotomy in the management of large angular deformities around the knee joint

“…Opening wedge osteotomy has the advantage of being a simple procedure, but it carries the risk of loss of fixation with subsequent collapse, delayed union and even non-union. Bone graft is usually required to enhance bone healing with this technique [3,6,8,9]. Closing wedge osteotomy is inherently stable and does not require special implant for its fixation, but it carries the risk of limb shortening and neurovascular compromise due to over tension of the soft tissue [4,[10][11][12].…”

Comparison between Autogenous Bone Graft and Allogenous Cancellous Bone Graft in Medial Open Wedge High Tibial Osteotomy with 2-Year Follow-up

“…However, due to the prolonged surgical time for graft harvesting, donor site pain, and the risk of inflammation17-19), allogenous bone grafts have been increasingly suggested as an alternative in domestic and foreign studies20-22). Their advantages over autogenous bone grafts include no concern for donor site pain and theoretically unlimited supply, whereas the disadvantages are low bone formation rate, the risk of spreading disease, and high cost.…”