Bone Augmentation and Simultaneous Implant Placement with Allogenic Bone Rings and Analysis of Its Purification Success

Abstract

The main objective of this manuscript was to demonstrate the use of freeze-dried bone allografts (FDBA) by means of a technique of simultaneous bone augmentation and implant placement (“Bone Ring Technique”) in different indications, i.e., ridge reconstruction and sinus floor elevation procedure with a maxillary bone height of less than 4 mm. Moreover, cases with an up to 3-year follow-up were chosen to analyze the techniques of mid-term clinical success. Finally, the purification success of the FDBA was analyzed by means of established scanning electron microscopic (SEM) and histological methods. The FBDA bone ring was applied in three different patients and indications and presented; the healing success was analyzed on the basis of radiographical and clinical images. For analysis of the purification of the allogeneic bone, previously established histological methods and scanning electron microscopy (SEM) were applied. All analyzed patient cases showed that the FDBA-based bone ring was fully integrated into newly built alveolar bone. Furthermore, the observations revealed that the three-dimensional bone reconstructions in maxilla and mandible were stable within the observational period of up to 3 years. Altogether, the present data show that the application of the Bone Ring Technique using the FDBA rings allows for successful regeneration of alveolar bone with a predictable clinical outcome, functionality and esthetics. Moreover, the material analyses showed that the allogeneic bone tissue was free of cells or cell remnants, while the (ultra-) structure of the bone matrix has been retained. Thus, the biological safety of the FDBA has been confirmed.

Balancing Purification and Ultrastructure of Naturally Derived Bone Blocks for Bone Regeneration: Report of the Purification Effort of Two Bone Blocks

“…In this context, it should be noted that the analyzed maxgraft ® block is produced by the Cells + Tissuebank Austria (C+TBA) that also provides bone blocks or bone substitutes for these latter applications. Interestingly, it has been revealed in different studies that these biomaterials allow for successful bone tissue repair [15,17]. However, further studies that include molecular biological methods should be conducted to analyze the impact of the described results on the process of bone tissue regeneration.…”

“…The histological analysis of the compositions of both bone blocks was also conducted following previously described methods [7,9,10,14,15]. Briefly, the histological slides of the bone substitutes were examined microscopically with respect to material characteristics such as the bone matrix structure and components like collagen or cells/cell remnants independently and blind by the two first authors using a light microscope Axio Scope.A1 (Carl Zeiss Microscopy GmbH, Jena, Germany).…”

Comparison of in‐situ bone ring technique and tent‐pole technique for horizontally deficient alveolar ridge in the anterior maxilla

“…Due to the strong osteogenic capacity, autogenous bone is still taken as the gold standard for the rehabilitation of alveolar ridge volume . The so‐called bone ring technique, as using a ring‐shaped autogenous bone block, has emerged recently and been documented in several medical records showing excellent outcomes for the dimensional bone augmentation . Nevertheless, most of the reports only emphasizes on the vertical augmentation and the existing proposal for horizontal bone augmentation is lack of investigation on the stability of the biomaterials and reflects drawbacks such as aggravating intraoperative pain due to the secondary surgical site and occurrence of the accompanying complications such as infection and paraesthesia of chin due to the incisal nerve injury …”

“…21 The so-called bone ring technique, as using a ring-shaped autogenous bone block, has emerged recently and been documented in several medical records showing excellent outcomes for the dimensional bone augmentation. [22][23][24][25] Nevertheless, most of the reports only emphasizes on the vertical augmentation and the existing proposal for horizontal bone augmentation is lack of investigation on the stability of the biomaterials and reflects drawbacks such as aggravating intraoperative pain due to the secondary surgical site and occurrence of the accompanying complications such as infection and paraesthesia of chin due to the incisal nerve injury. 26,27 Consequently, in this study, we mainly compared the volume alteration and bone profile maintenance ability between in-situ bone ring and tent-pole technique for the localized bone defect in anterior area to evaluate their effects on horizontal bone augmentation.…”

The Influence of Thrust Force on the Vitality of Bone Chips Harvested for Autologous Augmentation during Dental Implantation

“…A sufficient bone quality and quantity of the alveolar ridge is essential for the successful integration of a dental implant [1]. In the case of deficient alveolar ridges, bone volume can be increased by an augmentation with autologous bone rings [2] or autologous bone grafts, because the use of body´s own tissue is the safest and most compatible method for the patient [3,4]. For larger defects, whole bone blocks are transplanted, which have to be removed from the patient elsewhere [5].…”