Bone Deformation Recorded in vivo from Strain Gauges Attached to the Human Tibial Shaft

Lanyon, Lance E.; Hampson, W G; Goodship, Allen E.; Shah, JS

doi:10.3109/17453677508989216

Cited by 412 publications

(211 citation statements)

References 2 publications

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“…From the position of the calf muscles one might expect the anterior quadrant of the tibia to be subject to tension during loading; measurement of strain on the human tibia has shown large tensile strains on the tibia during running, though the loading direction does depend on the activity. 11 In experiments on fluid movement in bone, it has been shown that there is enhanced perfusion of the extracellular fluid space in bone in regions subjected to tension, 12 which suggests a role for bone-fluid flow in the bone changes seen in the SCI subjects. A significant decrease in the area of the cortical shell was seen in the chronic SCI group, but care must be taken when interpreting these values.…”

Section: Discussionmentioning

confidence: 99%

Changes in the structural and material properties of the tibia in patients with spinal cord injury

et al. 2011

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Study design: A cross-sectional study. Objectives: To measure the change of structural and material properties at different sites of the tibia in spinal cord-injured patients using peripheral quantitative computerised tomography (pQCT). Setting: Orthopaedic research centre (UK). Methods: Thirty-one subjects were measured-eight with acute spinal cord injury (SCI), nine with chronic SCI and fourteen ablebodied controls. pQCT scans were performed at 2% (proximal), 34% (diaphyseal) and 96% (distal) along the tibia from the tibial plateau. Structural measures of bone were calculated, and volumetric bone mineral density (vBMD) was also measured at all three levels. Muscle cross-sectional area was measured at the diaphyseal level. Results: Structurally, there were changes in the cortical bone; in the diaphysis, the shape of the cross-section changed to offer less resistance to AP bending, and the cross-sectional area of the cortical shell decreased both proximally and distally. There were corresponding changes in vBMD in the anterior aspect of the cortical diaphysis, as well as proximal and distal trabecular bone. Changes in muscle occurred more rapidly than changes in bone. Conclusion: There were clear changes of both structure and material at all three levels of the tibia in chronic SCI patients. These changes were consistent with specific adaptations to reduced local mechanical loading conditions. To assess fracture risk in SCI and also to monitor the effect of therapeutic interventions, the structure of the bone should be considered in addition to trabecular bone mineral density.

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Section: Discussionmentioning

confidence: 99%

Changes in the structural and material properties of the tibia in patients with spinal cord injury

et al. 2011

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“…Bone strain during very rigorous activities has never been measured in any animal. The only study which directly measured strain on a human bone in vivo was that by Lanyon et al (1975). These investigators bonded a strain gauge rosette to the anteromedial aspect of the tibia1 midshaft of a 35-year-old man.…”

Section: Fatigue Fracturementioning

confidence: 99%

Fatigue Behavior of Adult Cortical Bone: The Influence of Mean Strain and Strain Range

Carter¹,

Caler²,

Spengler³

et al. 1981

Acta Orthopaedica Scandinavica

341

135

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“…However, these studies could not account for muscle forces. Several studies attempted to measure in vivo deformation of the tibia during motion [6,24,31], but data were obtained for a limited number of points and not for the tibia and fibula together.…”

Section: Discussionmentioning

confidence: 99%

Tibia Adaptation after Fibula Harvesting: An in Vivo Quantitative Study

Taddei

Balestri

Rimondi

et al. 2009

Clinical Orthopaedics &Amp; Related Research

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Absence of the fibula after harvesting to reconstruct an upper-limb segment increases loads on the donor-side tibia and thereby provides a unique opportunity to analyze the bone adaptation process in humans. We therefore quantified densitometric and morphologic changes of the donor-side tibia in three young patients (ages 8, 13, 16 years), on the basis of computed tomography (CT) examinations of both legs (one preoperatively and two postoperatively). The range of final followup was 27-43 months. Three-dimensional models of shank bones were generated from CT data and used to measure crosssectional area, diaphyseal cortical thickness, and crosssectional moment of inertia. In addition, density of the newly formed bone was evaluated. The donor-side tibia showed morphologic and density adaptation with time.

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Bone Deformation Recorded in vivo from Strain Gauges Attached to the Human Tibial Shaft

Cited by 412 publications

References 2 publications

Changes in the structural and material properties of the tibia in patients with spinal cord injury

Changes in the structural and material properties of the tibia in patients with spinal cord injury

Fatigue Behavior of Adult Cortical Bone: The Influence of Mean Strain and Strain Range

Tibia Adaptation after Fibula Harvesting: An in Vivo Quantitative Study

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