Bone graft donor site infection with a rare organism, Aeromonas Hydrophila. A typical location, presentation and organism with 2 years follow-up. Case report

Hasan, Obada; Khan, Wajiha; Jessar, Muneeba; Pathan, Asad; Lakdawala, Riaz Hussain

doi:10.1016/j.ijscr.2018.08.037

Cited by 4 publications

(2 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Symptoms range from acute self-limiting diarrhea to lethal sepsis; however, wounds, skin, bones, heart, lungs, eyes, and other organs can be potentially affected ( Parker and Shaw, 2011 ; Ahmed et al, 2021 ; Meng et al, 2021 ). Most reports classify Aeromonas ’s human infections as events caused by “rare” or “uncommon” microorganisms ( Lai et al, 2007 ; Khalil et al, 2013 ; Hasan et al, 2018 ; Salehi et al, 2019 ). Indeed, other bacterial genus causing the same clinical symptoms are more frequent at hospital level.…”

Section: Introductionmentioning

confidence: 99%

Aeromonas and Human Health Disorders: Clinical Approaches

et al. 2022

View full text Add to dashboard Cite

The genus Aeromonas comprises more than 30 Gram-negative bacterial species and naturally inhabitants from aquatic environments. These microorganisms, commonly regarded as pathogens of fish and several other animals, have been gaining prominence on medical trial due to its ability to colonize and infect human beings. Besides water, Aeromonas are widely spreaded on most varied sources like soil, vegetables, and food; Although its opportunistic nature, they are able to cause infections on immunocompromised or immunocompetent patients. Aeromonas species regarded as potential human pathogens are usually A. hydrophila, A. caviae, and A. veronii biovar sobria. The main clinical manifestations are gastrointestinal tract disorders, wound, and soft tissue infections, as well as septicemia. Regarding to antibiotic responses, the bacteria present a diversified susceptibility profile and show inherence resistance to ampicillin. Aeromonas, as an ascending genus in microbiology, has been carefully studied aiming comprehension and development of methods for detection and medical intervention of infectious processes, not fully elucidated in medicine. This review focuses on current clinical knowledge related to human health disorders caused by Aeromonas to contribute on development of efficient approaches able to recognize and impair the pathological processes.

show abstract

Section: Introductionmentioning

confidence: 99%

Aeromonas and Human Health Disorders: Clinical Approaches

et al. 2022

View full text Add to dashboard Cite

show abstract

“…In 2018 to 2019, Hilt et al isolated several multi-drug resistant A. hydrophila isolates from two solid organ transplant patients [11]. In another case, Hasan et al recently reported the Aeromonas hydrophila infection in an immunocompromised 69 years old female, with surgical site sepsis/infection and several comorbidities [12].…”

Section: Introductionmentioning

confidence: 99%

Biological Characteristics and Genomic Analysis of Aeromonas Hydrophila Phage BUCT551 Isolated From Aquatic Sewage

Qin

et al. 2021

Preprint

View full text Add to dashboard Cite

Aeromonas hydrophila is a common opportunistic pathogen in aquaculture and is ubiquitous in aquatic environment. Whereby its accessibility, variety and host specificity, phage is increasingly considered as a promising complementary medicine for antibiotics. However, a small amount of A. hydrophila phages have been characterized, which suggests the significance to isolate and characterize novel A. hydrophila phages. In this study, we isolated a novel Aeromonas hydrophila phage using A. hydrophila strain A18 as an indicator and designated it as BUCT551, and it was identified as Myoviridae phage by transmission electron microscopy (TEM). The whole genome sequencing of the phage BUCT551 revealed that it has a linear DNA genome of 613,82 bp. BLASTn analysis showed that phage BUCT551 shared 86.75% homology with A. hydrophila phage LAh_7 (Genebank ID: MK838113.1). The one-step growth curve demonstrated that phage BUCT551 had a latent period of 20 min and the burst size of 32 pfu/cell at its optimal MOI of 0.1. The phage BUCT551 had a survival pH range from 5 to 10 and tolerant temperature from 0℃ to 40℃. Host range analysis shown that the phage was able to lyse not only A. hydrophila, but also A. veronii.

show abstract