Bone Marrow

Haddad, Jamie L.; Roode, Sarah C.; Grindem, Carol B.

doi:10.1016/b978-0-323-53314-0.00027-4

Cited by 2 publications

(1 citation statement)

References 39 publications

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“…Hierzu sollte die Entnahme jedoch innerhalb weniger Minuten (max. 30 Minuten nach dem Tod) stattfinden, um Autolyse und Zelldegeneration zu vermeiden [9].…”

Section: Merkeunclassified

Knochenmarkzytologie – Warum und wie?

Baur-Kaufhold

2023

kleintier konkret

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Bei richtiger Durchführung und gezielter Fragestellung ist die zytologische Beurteilung des Knochenmarks ein wichtiges Instrument zur Diagnosefindung. Dieser Artikel gibt einen kurzen Überblick über relevante Indikationen sowie wichtige präanalytische Faktoren für eine optimale Qualität der Probe. Was ist Knochenmark? Das Knochenmark (lat. Medulla osseum) befindet sich im Zentrum der (meist) großen Knochen (z. B. Sternum, Rippen, Becken sowie an den proximalen Enden von Humerus und Femur) [1, 2]. Es besteht aus einem schwammartigen, spezialisierten Binde-und Stammzellgewebe, das u. a. der Blutbildung dient. Man kann 2 Arten von Knochenmark unterscheiden: rotes und gelbes Knochenmark.

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“…Hierzu sollte die Entnahme jedoch innerhalb weniger Minuten (max. 30 Minuten nach dem Tod) stattfinden, um Autolyse und Zelldegeneration zu vermeiden [9].…”

Section: Merkeunclassified

Knochenmarkzytologie – Warum und wie?

Baur-Kaufhold

2023

kleintier konkret

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Tibial Plateau and Stifle Joint Invasion with a Subcutaneous Mast Cell Tumor

Triglia,

Horton,

Dobromylskyj

et al. 2023

Journal of the American Animal Hospital Association

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A 4 yr old female neutered Labrador retriever was referred with a history of left hind-limb lameness and an acute, nonpainful, subcutaneous mass on the medial aspect of the left stifle. Stifle radiographs and fine needle aspirates of the soft tissue mass performed by the referring veterinarian confirmed the presence of predominantly highly granulated mast cells, consistent with a mast cell tumor. Computed tomography demonstrated a soft tissue mass centered on the left medial stifle, with associated joint effusion and polyostotic lytic lesions on the tibial plateau and distal patella. Ultrasound-guided aspirates of the liver, spleen, and popliteal lymph nodes were obtained to rule out further metastatic spread. Cytology of the joint fluid demonstrated a low number of well-differentiated mast cells. Surgical and oncological interventions were discussed, and full hind-limb amputation was elected. Histopathological analysis of the submitted tissues after amputation diagnosed a subcutaneous mast cell tumor with neoplastic cell infiltrate extending into sections of joint capsule and synovial membrane. Infiltration to the tibia and distal patella were suspected following the presence of mast cell clusters in both osteolytic lesions. No evidence of metastasis was identified in the popliteal lymph node. Postoperative monitoring of iliac lymph node size using ultrasound did not identify evidence of metastasis 12 mo postoperatively.

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Bone Marrow

Cited by 2 publications

References 39 publications

Knochenmarkzytologie – Warum und wie?

Knochenmarkzytologie – Warum und wie?

Tibial Plateau and Stifle Joint Invasion with a Subcutaneous Mast Cell Tumor

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