Bone marrow metastases in salivary duct carcinoma of the parotid gland

Asarkar, Ameya; Takalkar, Amol; Dhawan, Manish; Nathan, Cherie Ann O.

doi:10.1136/bcr-2018-226636

Cited by 5 publications

(2 citation statements)

References 29 publications

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“…[ 3 , 4 ] Studies have reported metastasis to the bone marrow, breast, stomach, and gingiva. [ 9 – 12 ] However, there are no reports on the metastasis of SDC to the adrenal gland.…”

Section: Discussionmentioning

confidence: 99%

Solitary adrenal metastasis from salivary duct carcinoma of the parotid gland successfully treated by surgery

Amano¹,

Tsuji²,

Kihara³

et al. 2021

Medicine

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Rationale: Salivary duct carcinoma (SDC) is a rare and highly aggressive cancer with a poor prognosis. SDC demonstrates a potential for invasive growth with early regional and distant metastasis to organs, such as bone, lung, liver, and brain. Because, adrenal gland metastasis from SDC is rare, its treatment options are not well established. Herein, we report a case of SDC metastasis from the parotid gland to the adrenal gland, which was successfully treated by surgery. Patient concerns: The patient had an abnormal but painless lump on the right parotid gland. The size of the mass had increased over a period of 3 years. The patient underwent complete removal of the right parotid gland and radical neck dissection followed by adjuvant radiotherapy and chemotherapy. Two years later, a mass was identified in the left adrenal gland by computed tomography. As no local recurrence or metastasis to other organs was observed, the patient underwent adrenalectomy. Diagnoses: Metastasis of SDC in the adrenal gland was confirmed by histopathological examination of the adrenalectomized specimen. Interventions: After adrenalectomy, the patient was followed-up without adjuvant therapy. Outcomes: The patient was well and alive during the 13-month postoperative follow-up period without any complications. Lessons: Surgical resection of solitary metastatic lesion may show a survival benefit with metastatic SDC.

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“…[ 3 , 4 ] Studies have reported metastasis to the bone marrow, breast, stomach, and gingiva. [ 9 – 12 ] However, there are no reports on the metastasis of SDC to the adrenal gland.…”

Section: Discussionmentioning

confidence: 99%

Solitary adrenal metastasis from salivary duct carcinoma of the parotid gland successfully treated by surgery

Amano¹,

Tsuji²,

Kihara³

et al. 2021

Medicine

View full text Add to dashboard Cite

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“…The medical literature presents the case of a 53-year-old man with a medical history of parotid gland adenocarcinoma, treated with chemotherapy and radiation who came to present a metastatic adenocarcinoma lesion on the left side of the L4 vertebral body [4]. Likewise, another report cites the case of an 81-year-old woman with parotid gland cancer who underwent a total parotidectomy with facial nerve sacrifice and neck dissection, which, after surgery, was diagnosed with widespread metastases in the spinal cord bone [7]. Another study reports the story of a 70-year-old woman who underwent a total excision of the left parotid gland, cervical lymph node dissection and postoperative radiotherapy who, even so, died due to distant metastases 13 months after surgery [8].…”

Section: Discussionmentioning

confidence: 99%

Advanced Stage Stuck Gland Adenocarcinoma: Case Report

Baron¹,

Santos²,

Scherer³

et al. 2020

MRI

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Parotid gland adenocarcinoma is commonly a tumor of low malignancy and low incidence worldwide. The reported case shows the rapid progression of this tumor in an elderly patient and infrequent effects, such as a presentation of facial edema not commonly described in the medical literature. Patient was admitted to hospital in November 2019 with secretion and partial hearing loss in the right ear and infiltrative and stone lesion with initial skin ulceration in the right cervical region. After 42 days, he returned and was admitted to the intensive care unit with significant swelling of the face, hardened and hyperemic neck, difficulty in speech and inability to open the eye. He presented changes in the mobility of the speech and hearing organs, reduced laryngeal mobility, vocal changes, speech with altered articulation and severe oropharyngeal dysphagia with risk of bronchoaspiration. The patient was diagnosed in September 2019 with a parotid tumor (salivary gland adenocarcinoma T4). The medical team requested computed tomography, computed tomography angiography of the chest and cervical vessels and computed tomography of the neck, in addition to evaluation by the head and neck surgery service and general surgery. After analyzing the results, the medical team How to cite this paper: Baron, M.V., dos

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