2020
DOI: 10.21320/2500-2139-2020-13-3-273-279
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Bone Marrow Transplantation

Abstract: Natural killers (NK) were first described as large granular lymphocytes capable of destroying tumor and virus-infected cells without prior sensitization. The article deals with NK biology and specific features of their maturation and “licensing”. Particular attention is given to NK mechanisms and their differences from other lymphocytes. The article focuses on the role of NK in antitumor immune development in oncohematological patients as well as healthy individuals, potential bone marrow donors.

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