“…The progressive BM failure and the late developing myeloid malignancies account for 90% of the mortality in FA [1]. Aside from cord blood transplantation [2], the only cure for the hematopoietic manifestations of FA is an HLA identical allogeneic BM transplantation from a family member, a therapy available to only about 30% of patients [3]. Thirteen FA complementation types (FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ, FANCL, FANCM and FANCN) have been identified and the cDNAs of twelve FA genes have been sequenced .…”