Bone Mineral Content of Limb Bones of Male Weanling Rats Subjected to 30 and 60 Days of Simulated Increases in Body Weight

Abstract

The purpose of this study was to subject groups of male rats each to a specific 10% simulated increase in body weight, ranging from 1.1 to 2.0 g. Constant centrifugation was employed. After 30 and 60 days, rats were sacrificed and perfused with 10% BNF. The humerus, radius, ulna, femur, and tibia were removed, cleared of all soft tissues, weighed, decalcified with EDTA, and reweighed. Bone mineral content (BMC) was determined using the formula: [(W_u – W_d) ÷ W_u] × 100. Tukey’s multiple range test was used. The data suggest that male weanling rats subjected to simulated increases in body weight, within the range used in this study, undergo enhanced BMC, a bimodal curve describing the relationship between BMC and simulated increases in body weight.

Ultrastructure of the Parathyroid Gland of Magnesium-Treated Golden Hamster Exposed to a Hypergravity Environment: A Stereological Study

“…Many studies have shown the effects of a hypergravity environment on bone of animals (Rosenfeld et al , 1973;Fosse et al , 1974;Jaekel et al, 1977;Smith, 1977;Gazit, 1980;Pace et al, 1985;Simon et at., 1985;Wunder et al, 1987). In addition, ultrastructural reports have dealt with the problem on the influence of a hypergravity environment on the parathyroid gland (Sannes and Hayes, 1975; Shoumura et at., 1988a, 1989a, 1989b; Isono et al, 1990; Shoumura et al, 1990Shoumura et al, , 1991aShoumura et al, , 1991bShoumura et al, , 1992aShoumura et al, , 1992bShoumura et al, , 1992c.…”

Ultrastructural Studies on the Effects of Hypergravity Environment on the Parathyroid Glands in Golden Hamsters of Different Ages

“…1980;Pace et al. 1985;Simon et al. 1985;W underet al, 1987], and an increase in the bone density of animals exposed to hyper gravity has been documented [Amtmann and Oyama, this study was supported by a research grant from the Ministry of Hducation of Japan.…”

Ultrastructure of the Parathyroid Gland of Fetal and Pregnant Golden Hamsters Subjected to Hypergravity Environment

“…Many studies have shown the effects of a hypergravity environment on bone [1][2][3][4][5][6][7][8][9]. and morphological investiga tions have dealt with the problem concerning the effects of a hypergravity environment on the parathyroid gland [10][11][12][13][14][15][16][17], Many reporters have examined the ultrastructure of the parathyroid glands of mammalian fetuses and chick embryos under experimental conditions [18][19][20][21] as well as under normal conditions [22][23][24][25][26][27].…”