Bone Mineral Density in French Canadian Women

Abstract

This cross-sectional study investigated bone mineral density (BMD) at the lumbar spine (L2-4) and femoral neck in French Canadian women residing in the Quebec city area. Data collection was initiated in 1988 and completed in 1994. A total of 747 French Canadian Caucasian women (16-79 years of age) with no metabolic bone disease were evaluated. BMD measurements were obtained using dual-photon absorptiometry (DPA) or dual-energy X-ray absorptiometry (DXA). Anthropometric measures such as weight, height and body mass index (BMI) were recorded. Medical files provided information on demographic characteristics, hormonal profile and lifestyle habits. Results show a curvilinear trend of BMD with aging. Furthermore, the peak BMD at the lumbar spine (L2-4) was reached at 29 years followed by a stable phase until 35 years, after which BMD started to decrease. The pattern of bone evolution at the femoral neck was different, peak BMD being achieved earlier, at 21 years, while after age 26 years a significant decrease was already observed. Women older than 60 years showed the lowest BMD. Regression analysis showed that age, weight and height are determinants of BMD at the lumbar spine and explained 33.9% of inter-individual variation. At the femoral neck, 29.1% of variation was explained by age and height only. In conclusion, our data suggest that French Canadian women have a different pattern of bone loss at the femoral neck compared with the lumbar spine, according to their mean BMD values.

Normative data of bone Mineral Density in healthy population of Tehran, Iran: A Cross sectional study

“…On the other hand, the bone mass, physical activities and peak bone mass in men were more than women [25,26]. These results also indicate that the peak bone mass among women were in age of 30–39 which is in accordance with other studies [4-7,25-27]. The mean of spinal column BMD among women 30–39, was 5.6%lower than the American women, 3.9% more than the Japanese women 6.5% more than Filipino women,,0.06% more than Lebanese women [28,29].…”

“…The present study suggests that the maximum BMD of femur bone compared with spinal column occur later. This is justifiable considering the fact that the maximum BMD in cortical bone compared with trabecular bone occurs later [27,30,31]. The amount of BMD of spinal column was lower of 15.6% after ten years, and this reduction was 16.9% more than the Japanese women [33,35].…”

Hyperinsulinemia in nonobese women reporting a moderate weight gain at the beginning of menopause

“…This estimated figure is very close to the 61 kg measured in 627 premenopausal women aged 45 to 49 years who participated in the study on bone mass in our center. 23,24 In the HI women, the higher weight at time 5 years before their participation in the study and the superior weight gain during these 5 years were not different from those of the NI women. However, a significant difference was found between these two groups for the BMI estimated at time 5 years before the study.…”

Osteoporosis and fractures in Turner syndrome–importance of growth promoting and oestrogen therapy

“…(1994 ), who also stated that the reference levels given by the manufacturer are as good as many corrections used by various authors. The correlations between age, weight and height reported by Blanchet et al . (1998 ) for Canadian women were used in addition to calculate the expected BMD at the corresponding body size for the younger and older TS women of the present study.…”

“…GH and insulin‐like growth factor‐I (IGF‐I) stimulate bone growth ( Isaksson et al ., 1987 ). GH is important for height development and BMD correlates positively to height ( Blanchet et al ., 1998 ). Height also correlates positively with IGF‐I ( Landin‐Wilhelmsen et al ., 1994 ).…”