Bone permeability and mechanotransduction: Some current insights into the function of the lacunar-canalicular network

Murshid, Sakhr A.

doi:10.1016/j.tice.2022.101730

Cited by 4 publications

(3 citation statements)

References 117 publications

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“…The IFEM is able to influence the shape and function of cells and tissues. To give an example, the movement of these fluids in the bones in the lacunar-canaliculi network allows osteocytes to perceive and broaden the perception to mechanical stress, improving the mechanotransductive response [ 64 ]. The fluids between the osteocytes allow the same bone cells to communicate with each other, in response to the directional and pressure patterns of the fluids, thanks to the biochemical elements transported, and due to their ubiquity, any change in fluid displacement is immediately felt by the osteocytic cells [ 64 ].…”

Section: Reviewmentioning

confidence: 99%

“…To give an example, the movement of these fluids in the bones in the lacunar-canaliculi network allows osteocytes to perceive and broaden the perception to mechanical stress, improving the mechanotransductive response [ 64 ]. The fluids between the osteocytes allow the same bone cells to communicate with each other, in response to the directional and pressure patterns of the fluids, thanks to the biochemical elements transported, and due to their ubiquity, any change in fluid displacement is immediately felt by the osteocytic cells [ 64 ]. The osteogenic process has a greater impact not thanks to the direct mechanical deformation of the osteocyte membrane (the support of the foot on the ground), but thanks to the flow of fluids between the cells [ 64 ].…”

Section: Reviewmentioning

confidence: 99%

“…The fluids between the osteocytes allow the same bone cells to communicate with each other, in response to the directional and pressure patterns of the fluids, thanks to the biochemical elements transported, and due to their ubiquity, any change in fluid displacement is immediately felt by the osteocytic cells [ 64 ]. The osteogenic process has a greater impact not thanks to the direct mechanical deformation of the osteocyte membrane (the support of the foot on the ground), but thanks to the flow of fluids between the cells [ 64 ]. The IFEM works as a non-neural network, but with the same goal, that is, to communicate and receive.…”

Section: Reviewmentioning

confidence: 99%

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Fascial Nomenclature: Update 2022

Bordoni¹,

Escher²,

Tobbi³

et al. 2022

Cureus

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The connective tissue or fascia plays key roles in maintaining bodily function and health. The fascia is made up of solid and fluid portions, which interpenetrate and interact with each other, forming a polymorphic three-dimensional network. In the vast panorama of literature there is no univocal thought on the nomenclature and terminology that best represents the concept of fascia. The Foundation of Osteopathic Research and Clinical Endorsement (FORCE) organization brings together various scientific figures in a multidisciplinary perspective. FORCE tries to find a common nomenclature that can be shared, starting from the scientific notions currently available. Knowledge of the fascial continuum should always be at the service of the clinician and never become an exclusive for the presence of copyright, or commodified for the gain of a few. FORCE is a non-profit organization serving all professionals who deal with patient health. The article reviews the concepts of fascia, including some science subjects rarely considered, to gain an understanding of the broader fascial topic, and proposing new concepts, such as the holographic fascia.

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Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

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Fascial Nomenclature: Update 2022

Bordoni¹,

Escher²,

Tobbi³

et al. 2022

Cureus

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The innovative double or triple dental abutment‐implant: Case study with a 3‐to‐12‐year follow‐up

Colepícolo,

Mourão Martinez,

Rodrigues

et al. 2024

Clin Adv Periodontics

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BackgroundThe aim of this case study is to present the rationality and scientific evidence of a new design for a double (DA) and triple (TA) dental abutment‐implant with their specific new concept of biodynamic optimized peri‐implant tissue (BOPiT).MethodsThe innovative design of these abutments with a paraboloid geometry was based on BOPiT, simultaneously involving the principles of mechanobiology, biotensegrity, and mechanotransduction. Thus, 37 consecutive individuals/43 cases rehabilitated with single dental implant using the innovative DA (n = 28) and TA (n = 15) on 43 implants were included in this case study. The DA and TA support 2 or 3 dental crowns on a single implant, respectively. Clinic and radiographic examinations were presented at T1 (loading after 4 months) and T2 [final examination with an average follow‐up time of 7.2 years (>3 to 12 years)].ResultsAt T2, mean scores for plaque index, peri‐implant bleeding on probing, and peri‐implant probing depth were low, depicting healthy peri‐implant conditions. All radiographic images showed insignificant annual marginal bone loss (0.022 ± 0.05 mm) when compared to T1, reflecting great bone stability.ConclusionDA and TA, based on the BOPiT concept, represent an advantageous, simple and non‐invasive mechanism for the longevity and healthy regulation of the peri‐implant tissues.

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