2019
DOI: 10.2106/jbjs.18.00842
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Bone Repair Using the Masquelet Technique

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Cited by 212 publications
(238 citation statements)
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References 98 publications
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“…On the other hand, the Foucher-flap interruption of the Masquelet membrane with a fresh flap may result in bone resorption. 1 This phenomenon could be seen in our case after K-wire removal in the vicinity of the Foucher flap. Nevertheless, this had no significant impact on the final result, as the bone completely consolidated after further mobilization.…”
Section: Discussionsupporting
confidence: 66%
See 1 more Smart Citation
“…On the other hand, the Foucher-flap interruption of the Masquelet membrane with a fresh flap may result in bone resorption. 1 This phenomenon could be seen in our case after K-wire removal in the vicinity of the Foucher flap. Nevertheless, this had no significant impact on the final result, as the bone completely consolidated after further mobilization.…”
Section: Discussionsupporting
confidence: 66%
“…Masquelet technique is well known and well researched for treatment of extensive bone loss due to trauma, tumor, or infection. 1 It includes a 2-stage procedure. In the first step, meticulous surgical debridement is followed by implanting a polymethylmethacrylate (PMMA) spacer to cover the void while preserving neurovascular structures and healthy soft and bone issue.…”
Section: Introductionmentioning
confidence: 99%
“…At six to eight weeks, the PMMA block is removed, after which bone graft is placed in the defect. The exact mechanism of the membrane-associated osteoinduction has been the point of the ongoing discussion [10].…”
Section: Discussionmentioning
confidence: 99%
“…In particular, studies have observed that skeletal muscle aids fracture healing and subsequent remodeling through the provision of vascular derived mesenchymal stem cells, muscle stem cells, osteogenic myokines, and mechanical stimulation (see for review [46][47][48]), which manifest impaired simple fracture healing as well as rhBMP-2 mediated osteogenesis in a critical size segmental bone defect [49][50][51][52][53][54][55][56][57]. Supporting the clinical relevance of these basic science findings, severe open fractures can require more advanced fixation, soft tissue grafts or flaps, or multistep operative techniques (e. g. Masquelet technique [58]) to achieve union. Another significant factor playing a role in impaired fracture healing in the severely traumatized extremity is the heightened and prolonged inflammatory response that ensues.…”
Section: Fracture Healingmentioning
confidence: 99%