Echium amoenum, also named Gol-e-gavzaban in Persian, from boraginaceae family is one of the most commonly used medicinal plants, is distributed in the Northern region of Iran, as well as Europe and Mediterranean region. E. amoenum is traditionally used as herbal tea in Iranian traditional medicine for conditions such as common cold, bronchitis, stress and fatigue. It also possesses diaphoretic, diuretic and blood rectifying properties. The dried violet–blue petals of Iranian Borage are used as general tonic, cardiotonic, diaphoretic, diuretic, sedative and anti-tussive according to the Iranian Traditional Medicine (ITM). In this review article, the uses of E. amoenum as explained by Avicenna book II, Canon of medicine, book of Al-Adviah-Al-ghalbiah, and various databases of the latest scientific studies are discussed and compared. Using the experiences of old scientists in the botanical field and the properties of herbal medicines, as well as adapting new findings to old knowledge, can help us improve our understanding of prevention and treatment.It can also lead to obtain safe and cheap drugs. However, there are many common characteristics about the pharmacological properties of this plant in modern medicine and Iranian traditional medicine, but more research is needed to prove the safety and efficacy of the plant.