Borderline Brenner tumor with abnormally high serum level of carbohydrate antigen 199: a rare case report and literature review

Yu, Qianwei; Zhao, Qian; Su, Yuan; Xiong, Ke; Lü, Yan; Zhang, Lijiu; Hou, Fang

doi:10.1007/s11845-022-03203-7

Cited by 3 publications

(7 citation statements)

References 24 publications

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“…19 In clinical practice, detecting tumors in the early stages is essential by employing strategies for early diagnosis and early treatment. 3 The patient of the current study was followed up for 2 years after the surgery, in which no complication was reported. However, it is too early to determine the prognosis of the Brenner tumors.…”

Section: Discussionmentioning

confidence: 93%

“…Brenner tumor might be accompanied by abnormal elevation of serum CA19‐9 level. Hence, whenever there is no logical explanation for the increase in CA19‐9, the probability of a Brenner tumor should be considered by the attending physician 3 . However, CA 19‐9 is a highly utilized and well‐validated biomarker for the detection and diagnosis of pancreatic cancer, there is a possibility of detecting elevated CA 19‐9 levels in various forms of adenocarcinoma, particularly in advanced gastrointestinal malignancies 17 …”

Section: Discussionmentioning

confidence: 99%

“…Less than 60 studies regarding borderline Brenner tumors have been published to date, and there is minimal information regarding the favorable prognosis of the aforementioned tumors alone or with mucinous neoplasms 19 . In clinical practice, detecting tumors in the early stages is essential by employing strategies for early diagnosis and early treatment 3 …”

Section: Discussionmentioning

confidence: 99%

“…A Brenner tumor originally arises from the follicular epithelium and comprises ovarian transitional cells enclosed by fibrous tissue 1,2 . Based on the World Health Organization (WHO) classification, Brenner tumors are classified as benign, borderline, and malignant 3 . Brenner tumors are benign lesions, of which only 1% are malignant 4 …”

Section: Introductionmentioning

confidence: 99%

“…classification, Brenner tumors are classified as benign, borderline, and malignant. 3 Brenner tumors are benign lesions, of which only 1% are malignant. 4 Brenner tumors are generally asymptomatic and are observed incidentally; however, larger tumors might manifest themselves as pelvic mass compounded by severe pain.…”

mentioning

confidence: 99%

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Borderline Brenner tumor of the ovary with mucinous metaplasia: A case report

Shiravani,

Bahrami,

Najib

et al. 2023

Clinical Case Reports

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Key Clinical MessageTo date, there have been disparate reports regarding borderline forms of Brenner tumors, while research on concomitant mucinous proliferation is even more irregular; however, it has been observed that proper diagnosis and treatment have proven to have a favorable prognosis on the aforementioned tumor.AbstractBrenner tumor is a rare epithelial ovarian neoplasm responsible for 2%–3% of all ovarian tumors. These tumors are usually asymptomatic and can usually be found incidentally in pathological studies. They can also manifest themselves as abdominal pain or abnormal uterine bleeding. A 41‐year‐old female with a history of anemia referred to the hospital suffering from abdominal pain for at least 1 month before the referral period. Physical examination revealed a mobile palpable mass in the left lower abdomen. Ultrasound and pelvic computed tomography scan (CT scan) revealed a left ovarian complex cyst. Left salpingo‐oophorectomy was performed on the patient, and the cyst was removed. Pathological findings revealed an atypical proliferative Brenner tumor with mucinous metaplasia. To date, there have been disparate reports regarding borderline forms of Brenner tumors, while research on concomitant mucinous proliferation is even more irregular; however, it has been observed that proper diagnosis and treatment have proven to have a favorable prognosis on the aforementioned tumor.

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Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%