Boric acid gel enrichment of glycosylated proteins in human wound fluids

Kubutat, Caroline; Kyas, Andreas; Steinsträßer, L.; Jacobsen, Frank; Wolters, Dirk

doi:10.1016/j.jprot.2011.01.005

Cited by 11 publications

(9 citation statements)

References 14 publications

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“…For this purpose, a number of enrichment approaches have been developed, including lectin affinity, 386–387 hydrazide coupling, 388 HILIC, 389–390 and boronic acid affinity. 391–392 Among these strategies, lectin-affinity is the most widely used due to its high specificity. Lectins are carbohydrate binding proteins, which can specifically attach to sugar moieties.…”

Section: Ptm Analysis By Mass Spectrometrymentioning

confidence: 99%

Protein Analysis by Shotgun/Bottom-up Proteomics

et al. 2013

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Section: Ptm Analysis By Mass Spectrometrymentioning

confidence: 99%

Protein Analysis by Shotgun/Bottom-up Proteomics

et al. 2013

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“…It has been proposed that BCCs help preserve the structures of numerous macromolecular compounds, as well as the membrane and protein complexes [ 27 , 28 ]. Recent studies on mice have proved the interaction of BCCs with T- and B-cell receptors resulting in the proliferation of lymphocytes and the growing of the macrophages to release inflammatory mediators as a primary mechanism.…”

Section: ⧉ Discussionmentioning

confidence: 99%

Preclinical and histological study of boron-containing compounds hydrogels on experimental model of periodontal disease

Mitruț¹,

Cojocaru²,

Scorei³

et al. 2021

Rom J Morphol Embryol

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Periodontitis is a disease that affects a wide group of people, and there has been an increased interest in the research of finding useful materials that help reduce inflammation and the further loss of tissue. In this study, we have tested a boron-containing compound (BCC) Calcium Fructoborate (CaFB) and Boric Acid (BA) hydrogels on the gingival level on Wistar rats. First, we have induced the periodontal disease at the lower incisors, we have applied the hydrogels and after a week, we have euthanized the rats. Next, the oral soft tissue reaction was clinically and then histologically investigated. Our study has shown good clinical response of the oral tissue, and we have noticed lower levels of inflammation on the experimental groups treated with the BCCs hydrogels. Despite the generally good response of the biological structures to the presence of BA and CaFB on periodontal level, more scientifically proved information is needed to obtain the desired biological responses in all clinical situations.

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“…The vast majority of boron ore processing methods use ascharite as the raw material to produce borax and boric acid which are used as basic inorganic chemical raw materials and can be further processed into other boron compounds [14,15]. Previous studies have shown that the leaching rate of boron ore determines the complexity of preparing borax and boric acid, and that how to improve the leaching rate of boron ore therefore becomes a key scientific problem in the deep processing of boron ore resources [16][17][18][19]. After 60 years of deploitation and use, the grade of China's ascharite ore has been reduced, and the reserves are less than 2 million tons, with many mines depleted, so the reserves cannot meet the development needs of modern boron industry any more, creating a very prominent supply and demand contradiction.…”

Section: Introductionmentioning

confidence: 99%

Effects of sodium roasting on the leaching rate of boron-bearing tailings and its mechanism analysis

et al. 2018

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The study reported was intended to improve the leaching rate of boron-bearing tailings, using a method of sodium roasting that uses boron-bearing tailings as the raw material and Na2CO3 as the sodium agent. The effects of the roasting temperature and Na2CO3 amount on the leaching rate of boron-bearing tailings are mainly evaluated. The morphology and composition of the samples after sodium roasting are analysed by scanning electron microscopy and X-ray diffraction. The results show that sodium roasting can significantly improve the leaching rate of boron-bearing tailings. Under the optimal conditions where roasting temperature is 950°C, Na2CO3 amount is five times the theoretical amount and roasting time is 2 h, the leaching rate of boron-bearing tailings is up to 86.78%. Based on the analysis of the characterization results and the mechanism analysis of the sodium roasting process, the main reason for the increase of leaching rate is the reaction between Na2O produced by the decomposition of Na2CO3 and the boron in boron-bearing tailings resulting in soluble sodium borate. The results provide a scientific basis for the efficient comprehensive use of boron-bearing tailings.

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Boric acid gel enrichment of glycosylated proteins in human wound fluids

Cited by 11 publications

References 14 publications

Protein Analysis by Shotgun/Bottom-up Proteomics

Protein Analysis by Shotgun/Bottom-up Proteomics

Preclinical and histological study of boron-containing compounds hydrogels on experimental model of periodontal disease

Effects of sodium roasting on the leaching rate of boron-bearing tailings and its mechanism analysis

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