Boston type 1 keratoprosthesis from patient selection through postoperative management: a review for the keratoprosthetic surgeon

Williamson, Samantha; Cortina, María Soledad

doi:10.2147/opth.s83677

Cited by 3 publications

(1 citation statement)

References 34 publications

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“…Prior to surgery, the ocular surface must be carefully evaluated, as the survival period of the device is dramatically shortened, along with increased rates of complications, in eyes with poor ocular surface conditions [16]. The ideal recipient of the device should have adequate lid anatomy, blinking ability, and tear secretion.…”

Section: Preoperative Considerationsmentioning

confidence: 99%

Challenges in management of the Boston Keratoprosthesis Type 1

Koo

Hannush

2021

Current Opinion in Ophthalmology

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Purpose of reviewThe Boston Keratoprosthesis Type 1 was pioneered by Claes Dohlman several decades ago. Since its inception, the device has undergone multiple revisions to address challenges associated with retroprosthetic membrane formation, retention, extrusion, stromal melt and endophthalmitis. Although visual outcomes and retention rates have improved, challenges, especially glaucoma, remain. Recent findingsThe Boston Keratoprosthesis Type I device has seen an increase in popularity because of the improvement in rates of retention and visual rehabilitation. Recent outcome studies have allowed clinicians to identify diagnoses and indications that can lead to more favorable results with the Boston Keratoprosthesis Type I device.

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Section: Preoperative Considerationsmentioning

confidence: 99%

Challenges in management of the Boston Keratoprosthesis Type 1

Koo

Hannush

2021

Current Opinion in Ophthalmology

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Current Perspectives on Corneal Transplantation (Part 2)

Wong¹,

S²,

Walkden³

2022

OPTH

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Disease of the cornea is the third leading cause of blindness worldwide. Corneal graft surgery is one of the most successful forms of solid organ transplantations in humans, with ever increasing developments in surgical technique. To date, approximately 4504 corneal transplants are performed in the UK each year. While full thickness transplantation was the most commonly performed keratoplasty over the last few decades, selective lamellar transplantation of the diseased layers of the cornea has been universally adopted. This comprehensive review aims to provide an updated synthesis on different types of corneal transplantations, their treatment outcomes, and the associated complications of each procedure both in adult and pediatric populations. In addition, we also present an up-to-date summary of the emerging therapeutic approaches that have the potential to reduce the demand for donor-dependent keratoplasty.

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Post‑operative outcomes associated with Boston type 1 keratoprosthesis implantation in Northeast China

et al. 2018

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The aim of the present study was to investigate the post-operative outcomes associated with Boston type 1 keratoprosthesis (Kpro-1) implantation in the treatment of patients with corneal blindness in Northeast China. Clinical data of patients who had undergone Kpro-1 implantation between July 2010 and November 2014 were retrospectively collected. The visual performance, implant retention and post-surgical complications were recorded for each patient. A total of 20 patients (20 eyes) with corneal blindness were included in the study. Prior to surgery, the patients exhibited poor vision and decreased levels of light perception. At 3 days, 1 month, 6 months, 1 year and 2 years post-surgery, logarithm of the minimum angle of resolution values were significantly decreased compared with the pre-operative values. The initial Kpro-1 implants were retained in 16 eyes. Regarding the post-operative complications, six patients exhibited retroprosthetic membrane formation, two patients presented with endophthalmitis, two patients developed secondary glaucoma, two patients experienced optical cylinder detachment, two patients presented with corneal melting, three patients had retinal detachment, three patients developed corneal ulcers and one patient had secondary optic neuropathy. Overall, the results of the present study suggested that implantation with Kpro-1 may represent an alternative therapeutic strategy for patients following previously failed keratoplasty in Northeast China. Serious complications associated with Kpro-1 implantation are common, and thus, suitable patient selection, continuous follow-up and early treatment interventions are recommended.

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Boston type 1 keratoprosthesis from patient selection through postoperative management: a review for the keratoprosthetic surgeon

Cited by 3 publications

References 34 publications

Challenges in management of the Boston Keratoprosthesis Type 1

Challenges in management of the Boston Keratoprosthesis Type 1

Current Perspectives on Corneal Transplantation (Part 2)

Post‑operative outcomes associated with Boston type 1 keratoprosthesis implantation in Northeast China

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