“…Antigen surface expression, which can serve as a diagnostic tool (D'Arena et al, 2000;Huh et al, 2001;Olejniczak et al, 2006;Hulkkonen et al, 2002;Tam et al, 2008;Ginaldi et al, 1998); and 3. Antigen modulation during therapy, which can be indicative for durable therapeutic efficacy (Beers et al, 2010;Hiraga et al, 2009;Beum et al, 2006Beum et al, , 2008Williams et al, 2006;Czuczman et al, 2008;Bil et al, 2010;Boross et al, 2012).…”