On dielectric periodic structures with a reflection symmetry in a periodic direction, there can be antisymmetric standing waves (ASWs) that are symmetry-protected bound states in the continuum (BICs). The BICs have found many applications, mainly because they give rise to resonant modes of extremely large quality-factors (Q-factors). The ASWs are robust to symmetric perturbations of the structure, but they become resonant modes if the perturbation is non-symmetric. The Q-factor of a resonant mode on a perturbed structure is typically O(1/δ 2 ) where δ is the amplitude of the perturbation, but special perturbations can produce resonant modes with larger Q-factors. For twodimensional (2D) periodic structures with a 1D periodicity, we derive conditions on the perturbation profile such that the Q-factors are O(1/δ 4 ) or O(1/δ 6 ). For the unperturbed structure, an ASW is surrounded by resonant modes with a nonzero Bloch wave vector. For 2D periodic structures, the Q-factors of nearby resonant modes are typically O(1/β 2 ), where β is the Bloch wavenumber. We show that the Q-factors can be O(1/β 6 ) if the ASW satisfies a simple condition.