According to incomplete statistics from the Chinese Academy of Sciences in 2014, nearly 70 million people in China are sexual minorities. Among them, female sexual minorities, which account for a large proportion of the population, suffer from neglect and self-stigma because of the unequal treatment of women in traditional social culture, leading to negative well-being and health state. Starting from the causes of self-stigmatization, this study explores the feasible solutions to enhance resilience and prevent self-stigmatization of female sexual minorities in China and provides suggestions for female sexual minorities to establish their own organizations to help each other to provide them with source of confidence, social resources and social support. We hope that they are able live a better life through this research suggestions under the current special policies of the Chinese state.