In this paper, we deal with a chemotaxis‐haptotaxis model with re‐establishment effect. We consider this problem in a bounded domain Ω⊂double-struckRNfalse(N=2,3false) with zero‐flux boundary conditions. Although the L∞‐norm of the extracellular matrix density ω is easy to be obtained, the re‐establishment mechanism still cause essential difficulty due to the deficiency of regularity for ω. We use some iterative techniques to establish the W1,∞ bound of uPA protease concentration v, and further obtained the L∞ estimate of the cancer cell density u. Using these a prior estimates, we finally established the existence of global‐in‐time classical solution, which is bounded uniformly. The result of this paper fills the gap of [Pang and Wang, J. Differential Equations 263 (2017) 1269–1292; Tao and Winkler, J. Differential Equations 257 (2014) 784–815] in dimension 2 with q=1, in [Tao and Winkler, J. Differential Equations 257 (2014) 784–815], the boundedness of the solution is left open; and in [Pang and Wang, J. Differential Equations 263 (2017) 1269–1292], the global existence and boundedness is established only for large μ. In particular, the global solvability and boundedness of smooth solutions in dimension 3 has never been touched before, this paper is the first attempt to solve this problem.