In the present paper, we will characterize the boundedness of the generalized fractional integral operators I ρ and the generalized fractional maximal operators M ρ on Orlicz spaces, respectively. Moreover, we will give a characterization for the Spanne-type boundedness and the Adams-type boundedness of the operators M ρ and I ρ on generalized Orlicz-Morrey spaces, respectively. Also we give criteria for the weak versions of the Spanne-type boundedness and the Adams-type boundedness of the operators M ρ and I ρ on generalized Orlicz-Morrey spaces.