Bowel abnormalities in the fetus - Correlation of prenatal ultrasonographic findings with outcome

Corteville, Jane E.; Gray, Diana L.; Langer, Jacob C.

doi:10.1053/ob.1996.v175.a74412

Cited by 77 publications

(56 citation statements)

References 11 publications

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“…Wax et al [12] suggested that the presence of both an enlarged stomach and polyhydramnios should raise the suspicion of jejunal atresia rather than ileal atresia. Corteville et al [15] showed huge differences in the prenatal detection rate between proximal and distal intestinal atresia (100 vs. 8%). In line with Haeusler et al [14] we could not find any differences in the detection rate between jejunal and ileal atresia.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Accuracy of Prenatal Ultrasound in Identifying Jejunal and Ileal Atresia

et al. 2015

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Introduction: Small bowel atresia (SBA) is one of the most common causes of congenital intestinal obstruction. However, the accuracy of prenatal ultrasound in diagnosing this condition has not been entirely ascertained. The aim of this study was to analyse the predictive accuracy of ultrasound in detecting SBA prenatally. Methodology: Retrospective study of all cases with prenatal suspicion or postnatal confirmed SBA seen in a tertiary fetal medicine and pediatric surgery units from 2007 to 2013. Cases with duodenal atresia were excluded from the study. The predictive accuracy of ultrasound and different ultrasound signs, alone and in combination, was calculated. Results: 65 fetuses with prenatal suspicion or postnatal confirmed SBA were enrolled. 58 cases had full data and were included in the analysis. Predictive accuracy of ultrasound in detecting the presence of SBA was poor, with a sensitivity of 50% (95% CI 26.0-74.0) and a specificity of 70.59% (95% CI 52.5-84.9). The presence of both bowel dilatation ≥17 mm and polyhydramnios after 32 weeks of gestation slightly increased sensitivity (66.67%, 95% CI 34.9-90.1) and specificity (80.00%, 95% CI 44.4-97.5). Conclusions: In case of suspicion of SBA before the 3rd trimester, an ultrasound after 32 weeks should be performed to confirm the presence of both polyhydramnios and bowel dilatation >17 mm.

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Section: Discussionmentioning

confidence: 99%

Diagnostic Accuracy of Prenatal Ultrasound in Identifying Jejunal and Ileal Atresia

et al. 2015

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“…At sonography, overt dilatation of the fetal bowel loops is generally a sign of anatomic obstruction [5,6] . We herein report 2 cases in which dilatation of the fetal bowel was not associated to anatomic obstruction but was apparently caused by paralytic ileum.…”

Section: Discussionmentioning

confidence: 99%

Transient Bowel Ischaemia of the Fetus

Ghi

Tani²,

Carletti³

et al. 2004

Fetal Diagn Ther

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Objective: To discover the different underlying conditions in 2 fetuses suffering from temporary bowel ischaemia. Methods: Abnormal bowel findings were detected using antenatal sonography. Results: The abnormal bowel findings disappeared postnatally. Transient ischaemia of the fetal bowel due to different causes has been advocated antenatally to explain the abnormal findings. When a normal blood supply to the bowel has been restored, either in utero or after birth, the abnormal findings disappear. Conclusions: Whenever gut dilatation is detected in a fetus at risk of bowel ischaemia the possibility of a transient functional finding must be considered.

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“…In addition to karyotyping, sampling of fetal blood can exclude anemia or intrauterine infections, either by measurement of titers or DNA probes. Genetic analysis of cystic fibrosis should be done if ascites presents in combination with intestinal pathologies [11,12]. We recommend that a systematic protocol for diagnostic workup of fetal ascites should be followed.…”

Section: Discussionmentioning

confidence: 99%

Etiology and Prognosis of Fetal Ascites

et al. 2003

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Objective: To examine the prenatal course and outcomes of neonates with isolated fetal ascites. Methods: A retrospective analysis (from 1990 through 2000) was performed on 26 consecutive cases presenting with fetal ascites. A systematic diagnostic protocol which included fetal blood sampling for karyotyping, serology and serial ultrasound examinations to determine etiology was followed in all cases after diagnosis. Pregnancy outcome was assessed by a chart report or autopsy reports. Results: The majority of cases were associated with fetal malformations (n = 11). Five fetuses had malformations with associated syndromes. Less commonly associated were intrauterine infections (n = 3), intestinal perforation (n = 2), genetic disorders (n = 2), neoplasm (n = 1) and growth retardation (n = 1). In only 1 case (4%) was the etiology idiopathic. Secondary generalized hydrops occurred only in 4 of 26 cases. Only 13 of 16 liveborn infants survived past the neonatal period and only 4 cases are doing well at childhood age without any sequelae. Conclusion: A wide range of etiologies were associated with isolated fetal ascites. Those with malformations had the worst pregnancy outcome. Prenatal diagnosis was made in 92% utilizing a systematic diagnostic workup. The diagnosis of idiopathic ascites has become rare due to the improvement in prenatal diagnosis.

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Bowel abnormalities in the fetus - Correlation of prenatal ultrasonographic findings with outcome

Cited by 77 publications

References 11 publications

Diagnostic Accuracy of Prenatal Ultrasound in Identifying Jejunal and Ileal Atresia

Diagnostic Accuracy of Prenatal Ultrasound in Identifying Jejunal and Ileal Atresia

Transient Bowel Ischaemia of the Fetus

Etiology and Prognosis of Fetal Ascites

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