Bowel perforation after paediatric orthotopic liver transplantation

Melendez, Hector Vilca; Vougas, V.; Muiesan, Paolo; Andreani, P.; Mieli‐Vergani, Giorgina; Rela, Mohamed; Heaton, Nigel

doi:10.1007/s001470050146

Cited by 30 publications

(26 citation statements)

References 9 publications

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“…Current literature is scant on intestinal perforations, and most are anecdotal reports. We showed here that the incidence of intestinal perforation in adult liver transplant recipients was 2.7%, which is consistent with previous studies reporting an incidence of 1% to 5.3% for adult intestinal perforations after orthotopic liver transplantation 3–6. The reported incidence in this study is similar to that by Xiong et al1 who studied 187 Chinese adult liver transplant recipients and detected an incidence of 3.2%.…”

Section: Discussionsupporting

confidence: 92%

Treatment and outcome of intestinal perforation after liver transplant surgery in adults: a single-center experience

Lin¹,

Wang²,

Yue³

et al. 2017

TCRM

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ObjectiveIntestinal perforation is a rare complication after liver transplantation. This study was designed to calculate the incidence and investigate the outcomes of intestinal perforation in adult liver transplant patients.Materials and methodsThe clinical records of liver transplant recipients between January 2014 and June 2016 were obtained. The incidence of intestinal perforation was calculated, and high risk factors were analyzed.ResultsThe mean operative time was 8.5 h (range: 6–11 h). The mean portal vein occlusion time was 66.5 min (range: 58–72 min), and the mean cold ischemia time was 7.9 h (range: 6.5–9.5 h). Four (2.7%) patients developed intestinal perforation from 9 to 14 days postliver transplant. All perforations were single and repaired by interrupted silk sutures. Two patients uneventfully recovered, but intestinal perforation recurred in two other patients. Simple repair was undertaken in one patient, and terminal ileum resection and ileostomy were performed in the other patient. There were no perioperative deaths.ConclusionThe incidence of intestinal perforation after liver transplantation is low. Prompt diagnosis and treatment should be carried out to reduce comorbidities and mortality.

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Section: Discussionsupporting

confidence: 92%

Treatment and outcome of intestinal perforation after liver transplant surgery in adults: a single-center experience

Lin¹,

Wang²,

Yue³

et al. 2017

TCRM

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“…The incidence is higher (15%) in children who have undergone transplantation for biliary atresia after Kasai portoenterostomy [37].…”

Section: Bowel Perforationmentioning

confidence: 99%

Liver transplantation in children

Muiesan

Vergani

Mieli‐Vergani

2007

Journal of Hepatology

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“…Intestinal perforation is reported to occur in 4%–20% of children undergoing LT for biliary atresia124, 125 and should be suspected in cases of unexplained sepsis or clinical deterioration. Treatment for presumed fungal infection should also be strongly considered in these cases 126.…”

Section: Surgical Approaches In Transplantation For Biliary Atresiamentioning

confidence: 99%