Bowen′s disease on finger: A diagnostic and therapeutic challenge

Singh, Saurabh; Khaitan, Binod K.; Sharma, Mehar Chand; Seenu, Vuthaluru; Kumawat, Mahesh; Chatterjee, Priti

doi:10.4103/0378-6323.107643

Cited by 7 publications

(3 citation statements)

References 12 publications

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“…13 Massimiliano et al conducted a study on 182 patients where most of the lesions presented as slow enlarging, well demarcated erythematous to pink patch/plaque with irregular borders and scaly surface and crusting. 14 Sahra and Hayadeh et al did a study on five patients and almost all patients presented with erythematous plaque with dark red papules. 15 Our study conducted on 14 patients also showed erythematous scaly plaques/patch as the important presenting feature in 80% of the cases.…”

Section: Discussionmentioning

confidence: 99%

Bowens disease: clinico pathological correlation with review of literature

A.,

Joseph,

Priyadarshini

2024

Int J Res Dermatol

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Bowen’s disease is a type of squamous cell carcinoma in situ. It is most frequently diagnosed in the sixth to eighth decade of life. However, there have also been a few reports of pigmented Bowen’s disease. A single or multiple erythematous, round to irregular, scaly, keratotic, nodular, pigmented patches/plaques are first signs of the lesion. All cases of Bowen’s disease presented at a tertiary care centre over a period of seven years were included in this study. The patient details and clinical history were obtained from medical records. Histopathological slides of these cases were reviewed and analyzed. There were fourteen cases of Bowen’s disease with most patients belonging to 5-6th decade of life (80%). Males were more commonly affected (60%). Duration of the lesion ranged between 3-5 years in 60% of the patients. Most common site involved was lower back (80%). Most common presenting feature was hyperpigmented, erythematous plaques with scaling seen in 90% of the patients. Epidermal changes such as marked acanthosis with full thickness atypia were noted in 90 % and hyperkeratosis, parakeratosis was noted in 70% of the patients. Lichenoid infiltrates at dermo-epidermal junction was noted in 70% cases. The correct identification helps in appropriate diagnosis and treatment after biopsy confirmation. Adequate resection helps in preventing risk of invasive malignancy in these conditions.

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Section: Discussionmentioning

confidence: 99%

Bowens disease: clinico pathological correlation with review of literature

A.,

Joseph,

Priyadarshini

2024

Int J Res Dermatol

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“…Bowen's disease, also known as squamous cell carcinoma in situ, is a common malignant skin tumor that usually manifests as solitary plaques on the head, neck, and lower extremities, 1 with multiple rashes in a few cases 2 . Risk factors for Bowen's disease include ultraviolet radiation, human papillomavirus (HPV) infection, 3 arsenic exposure, 4 human immunodeficiency virus (HIV) infection, 5 and other forms of immunosuppression 6 .…”

Section: Introductionmentioning

confidence: 99%

Multiple Bowen's disease due to long‐term narrow‐band ultraviolet B phototherapy: A case report and literature review

Zhang,

Fan,

Liu

et al. 2024

J of Cosmetic Dermatology

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ObjectiveBy presenting a case study on multiple instances of Bowen's disease and the consistent use of narrow‐band ultraviolet B (NB‐UVB) phototherapy over a three‐year period, our aim is to enhance the comprehension of domestic clinicians regarding the disease. Additionally, we seek to review existing literature, encouraging dermatologists to consider clinical secondary primary lesion diagnoses.MethodOur approach involves analyzing a diagnosed case of multiple Bowen's disease, examining clinical manifestations, histopathology, imaging results, and treatment methods related to NB‐UVB phototherapy. We aim to facilitate discussion and understanding through a comprehensive literature analysis.ResultsAn elderly male with a 30‐year history of psoriasis vulgaris initiated continuous NB‐UVB therapy three years ago. A year later, he developed red patches and plaques with distinct borders and scaly surfaces on his face, trunk, lower extremities, and scrotum. Histopathological examination confirmed Bowen's disease. Treatment involved liquid nitrogen cryotherapy, with no recurrence observed during the one‐year follow‐up.ConclusionThis case highlights that Bowen's disease, typically solitary, can manifest as multiple instances, especially in individuals with a history of psoriasis vulgaris. While NB‐UVB stands as the primary treatment for psoriasis vulgaris, caution is warranted due to the potential risk of skin tumor induction with prolonged high‐dose usage. Clinicians should be vigilant in monitoring and assessing the long‐term implications of such therapies.

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“…Bowen's disease (BD) is a rare, progressive, intraepithelial neoplastic condition first described by John Templeton Bowen in 1912 [1]. The risk of development of invasive carcinoma is 3%-5% in extra genital lesions and 10% in genital lesions [2].…”

Section: Introductionmentioning

confidence: 99%