Brachial-ankle pulse wave velocity and blood pressure control in treated hypertensive patients

Kawada, Tomoyuki

doi:10.1016/j.ijcard.2015.03.028

Cited by 1 publication

(1 citation statement)

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“…Most studies on baPWV-associated factors have focused on patients with hypertension and the other diseases mentioned above [11][12][13][14], but arterial stiffness is not confined to patients with hypertension. In nonhypertensive individuals, it is not clear whether blood pressure (BP) has an effect on baPWV.…”

Section: Introductionmentioning

confidence: 99%

Factors Associated with Brachial‐Ankle Pulse Wave Velocity in an Apparently Healthy Chinese Population

Chen

Liu

Jia

et al. 2020

BioMed Research International

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Purpose. To investigate the factors influencing brachial-ankle pulse wave velocity (baPWV) in an apparently healthy Chinese population, especially the associations between baPWV and indices of blood pressure (BP). Methods. A total of 1123 participants with no history of hypertension were enrolled in this study, and the baPWV and BP of all four limbs were measured along with other covariates. Correlation analyses and multivariate linear regression models were used to identify factors associated with baPWV. Results. A total of 1123 participants (male 43.3%, mean age: 58.4±13.9 years) were included. The average baPWV was 14.87±3.21 m/s, and no difference was found between the sexes. Age was positively correlated with baPWV (r=0.65, p<0.01), especially in females (r=0.71 versus 0.56 in males). The correlation coefficient between age and baPWV increased markedly after the age of 65 years. In addition, the resting heart rate (RHR), waist-hip ratio, glomerular filtration rate, and plasma glucose level were significantly correlated with baPWV (r=0.25, 0.22, -0.43, and 0.25, respectively; p<0.01). BP parameters were highly positively correlated with baPWV, especially systolic BP (SBP) and pulse pressure (PP). Multivariate regression revealed that age, BP parameters, and RHR were independently correlated with baPWV (p<0.01) after adjusting for confounding factors. The standardized coefficients of SBP were greater than those of PP, followed by diastolic BP (DBP). Conclusion. BaPWV increased with age, especially after 65 years. Age, BP, and RHR were independent factors associated with baPWV. The effect of SBP on baPWV was more prominent than that of PP.

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Section: Introductionmentioning

confidence: 99%