Bradycardia as the First Sign of Brain Tumor: A Case Report

Kamil, Ammar; Ghazzay, Hazim

doi:10.14740/jmc3032w

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…It accounts for < 2% of all glioma and 5% of all astrocytomas [71]. Early brain tumor could manifest rst sign as bradycardia [72]. Meningiosarcoma (cerebral sarcoma) was treated in a 3-year-old boy by surgery and radiation and 55 years later, rebonced, suggesting that comprehensive medical history could reveal early diagnosed pediatric brain tumors [73].…”

Section: Discussionmentioning

confidence: 99%

Comparative Parameters of Occult and Multiple Brain Tumors In Human: The Implication for Therapy

Saganuwan

2021

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Background Brain cancer treatment is a difficult task, because of complex nature of physico-chemical properties of brain, central nervous system (cns) acting drugs and drug carriers. Methods In view of this, literatures were searched with a view to assessing comparative mathematical parameters of occult and multiple primary brain tumors and their therapeutic outcomes. A total of thirteen patients comprised of eight males and five females who had suffered either occult or multiple brain tumors were used for the study. Tumor parameters and their therapeutic prognoses were mathematically determined. The data were analyzed using a modified Kaplan-Meier method at 5 % level of significance. Results Findings have shown that occult tumors such as meningiosarcoma (65.4cm3), teratoma (268 cm3), solitary brain tumor (20.6–22.4 cm3) and gliosarcoma (31.1 cm3) as well as multiple primary brain tumors; meningioma/diffuse astrocytoma (47.7 cm3), glioblastoma multiforme/pituitary adenoma (164. 59 cm3) and planum sphenoidale meningioma/pituitary adenoma (26.52 cm3) are deadly. However solitary brain tumor (4.2 cm3), glioblastoma multiforme/pituitary adenoma (12.77 cm3) and multimeningioma/pituitary adenoma (0.70 cm3) have high survival rate. Generally tumor weight (4.2–144.0 g), tumor density (0.24–0.96), total population of tumor cells (9.5 x 108-2.5 x 1011, rate of tumor cell migration (1.10–48.0 cm2/yr) and tumor radius (0.55-4.0 cm) are relatively moderate to very high, signifying that occult brain tumors may generate faster and may be more difficult to treat chemotherapeutically, radiotherapeutically, immunologically and surgically. Brain tumors affect male and female of 2–79 years old. Conclusions The locations of tumors are parietal, temporal, frontal, thalamic, frontoparietal, stellar, and planum sphenoidale lobes. Both occult and multiple brain tumors are diagnosed when all forms of therapy would have been useless.

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Section: Discussionmentioning

confidence: 99%

Comparative Parameters of Occult and Multiple Brain Tumors In Human: The Implication for Therapy

Saganuwan

2021

Preprint

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Syncope as a sign of occult cancers: a population-based cohort study

et al. 2019

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Background We examined if syncope was a marker of an occult cancer by comparing the risk in patients with a syncope episode with that of the general population. Methods Using Danish population-based medical registries, we identified all patients diagnosed with syncope during 1994–2013 and followed them until a cancer diagnosis, emigration, death or end of follow-up, whichever came first. We computed cumulative risks and standardised incidence ratios (SIR) with 95% confidence intervals (CI). Results Among 208,361 patients with syncope, 20,278 subsequent cancers were observed. The 6-month cumulative risk of any cancer was 1.2%, increasing to 17.9 % for 1–20 years of follow-up. The highest cumulative risks after 6 months of follow-up were lung cancer (0.2%), colorectal cancer (0.2%), prostate cancer (0.1%) and brain cancer (0.1%). The 6-month SIR were 2.7 (95% CI: 2.4–3.0) for lung cancer, 2.0 (95% CI: 1.8–2.2) for colorectal cancer, 1.7 (95% CI: 1.5–1.9) for prostate cancer and 10.0 (95% CI: 8.6–11.4) for brain cancer. Conclusions Syncope was a weak marker of an occult cancer. In short-term the highest cumulative risks were observed for lung, colorectal, prostate and brain cancers. An aggressive search for occult cancer in a patient with syncope is probably not warranted.

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Bradycardia as the First Sign of Brain Tumor: A Case Report

Cited by 2 publications

References 12 publications

Comparative Parameters of Occult and Multiple Brain Tumors In Human: The Implication for Therapy

Comparative Parameters of Occult and Multiple Brain Tumors In Human: The Implication for Therapy

Syncope as a sign of occult cancers: a population-based cohort study

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