Bradycardiac Angina: Haemodynamic Aspects and Treatment

Fowler, P.B.S.; Ikram, Hamid; Maini, R. N.; Makey, A. R.; Kirkham, J.S.

doi:10.1136/bmj.1.5636.92

Cited by 14 publications

(4 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was suggested by Fowler et al (1969) that the pathology of sinoatrial node disorder might be comparable with that found in idiopathic heart block and indeed atrophy and fibrosis do occur in the latter condition. Furthermore, the changes detected in this series were not limited to which contains injectate, has split into 2 branches.…”

Section: Discussionmentioning

confidence: 92%

Pathological studies in sinoatrial disorder (sick sinus syndrome).

Evans¹,

Shaw²

1977

Heart

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 92%

Pathological studies in sinoatrial disorder (sick sinus syndrome).

Evans¹,

Shaw²

1977

Heart

View full text Add to dashboard Cite

“…Thus in 1 series, 61 per cent of patients were considered to have coronary artery disease, yet a past history of myocardial infarction was present in only 20 per cent (Hartel and Talvensaari, 1975). Presumably most of the rest were diagnosed on the basis of angina of effort, but some believe that this may itself be a manifestation of the bradycardia (Fowler et al, 1969). Postmortem coronary angiography and histological examination of the sinoatrial node should be the final arbiters.…”

Section: Discussionmentioning

confidence: 99%

Potential candidates for pacemakers. Survey of heart block and sinoatrial disorder (sick sinus syndrome).

Shaw¹,

Kekwick²

1978

Heart

View full text Add to dashboard Cite

SUMMARY Future pacemaker requirements in Britain are related to the incidence of heart block and sinoatrial disorder (sick sinus syndrome) in the community. This paper reports an 8-year survey of these conditions by direct approach to the general practitioners looking after approximately 600 000 people. The patients were divided into 4 non-exclusive groups (numbers of patients are in parentheses); chronic complete heart block (436), sinus bradycardia (potential and established sinoatrial disorder) (305), established sinoatrial disorder (131), and paced patients (209). Patients with sinoatrial disorder and sinus bradycardia were some 10 years younger than those with heart block and their prevalence tended to decline in the very old, whereas the prevalence of heart block continued to increase almost exponentially, exceeding 5 per 1000 in men aged 80 and above.Only a minority of patients gave a past history of cardiac infarction or diphtheria, but both conditions were commoner in sinoatrial disorder (16% and 14%, respectively) than in complete heart block (9% and 8%, respectively). A surprising finding was that men predominated in all groups, particularly in those with sinus bradycardia where the male:female ratio was 2-5:1. The annual number of new paced patients rose during the course of the survey, reaching 73 per million (per year) by the seventh and eighth years, but the annual incidence of conditions producing bradycardia and potentially requiring pacemaker therapy was still much greater at 159 to 174 per million of the population.In Britain the number of initial implantations of cardiac pacemakers has almost trebled since 1972 and it is predicted that there will be a further threefold increase in the next 5 years (Sowton, 1976). In view of this dramatic rise in the use of such expensive and sophisticated equipment it might be expected that the incidence and aetiology of the main conditions requiring pacemaking, namely heart block and sinoatrial disorder, would be well known, but in fact the lack of epidemiological data on heart block has been bewailed by Campbell as recently as 1977. Data on sinoatrial disorder are even more scarce (British Medical journal, 1977), while the problem is compounded by the absence of a clear-cut definition of the condition. In the past coronary artery disease was blamed for both chronic heart block and sinoatrial disorder, and if this were correct the current 'epidemic' of ischaemic heart disease should be followed by an increase in their

show abstract

“…This formula resulted in some original descriptions of disease, including printer's asthma, 1 caused by allergy to gum acacia used as a print set-off spray, and bradycardiac angina. 2 He coauthored research on the potential of the ganglion blocking agent hexamethonium to prevent heart failure 50 years before β adrenergic blocking drugs were to become routine therapy for patients with heart failure. 3 He completed his MD thesis while working with Donald Hunter on resettling disabled people.…”

mentioning

confidence: 99%

P B S Fowler

Savage¹

2011

BMJ

View full text Add to dashboard Cite

Bradycardiac Angina: Haemodynamic Aspects and Treatment

Cited by 14 publications

References 6 publications

Pathological studies in sinoatrial disorder (sick sinus syndrome).

Pathological studies in sinoatrial disorder (sick sinus syndrome).

Potential candidates for pacemakers. Survey of heart block and sinoatrial disorder (sick sinus syndrome).

P B S Fowler

Contact Info

Product

Resources

About