Bradykinin and the bacterium-phagocytosis of leucocytes

Ludány, G; Vajda, Júlia; Bertha, I

doi:10.1007/bf00680188

Cited by 2 publications

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“…The stimulation of phagocytosis ability of granulocytes by BK has been found to be 50 times higher than that by histamine and 100 times higher than that by 5-HT [143]. As early as 1967, BK has been shown to stimulate the phagocytosis ability of leukocytes.…”

Section: Immune Systemmentioning

confidence: 91%

Kinin Receptors and Their Antagonists as Novel Therapeutic Agents

Öztürk

2001

CPD

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Plasma kinins are a family of peptides which play an important role in a variety of pathophysiological conditions. As a consequence of the progress in the area of kinin receptors, specific kinin receptor antagonists will be available in near future in order to provide more selective therapeutic modalities for the treatment of diseases such as asthma, cardiovascular diseases, inflammation, pain, etc. Although the initial observation leading to discovery of kinins has been performed in 1909, important progress on the development of specific kinin receptor antagonists has been made in last two decades. This review emphasizes the physiological functions of kinins along with their receptor subtypes and post-receptor events in the cellular signaling. In this article, the latest developments in the kinin receptor antagonists including nonpeptide ones have been reviewed.

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Section: Immune Systemmentioning

confidence: 91%

Kinin Receptors and Their Antagonists as Novel Therapeutic Agents

Öztürk

2001

CPD

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“…However, plasma kinins cause margination of leukocytes (155,156). Bradykinin significantly enhances leukocyte phagocytosis of bacteria in vitro (160). Bradykinin in small doses increases reticuloendothelial function, but is inhibitory in high doses (147).…”

Section: Polypeptidesmentioning

confidence: 99%

Leukocytic Mechanisms in Inflammation

Hersh¹,

Bodey²

1970

Annu. Rev. Med.

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Bradykinin and the bacterium-phagocytosis of leucocytes

Cited by 2 publications

References 0 publications

Kinin Receptors and Their Antagonists as Novel Therapeutic Agents

Kinin Receptors and Their Antagonists as Novel Therapeutic Agents

Leukocytic Mechanisms in Inflammation

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