Brain Abscess Due to<i>Nocardia</i>in a Patient With Systemic Lupus Erythematosus

Li, Zhuoxuan; Li, Dongling; Lv, Pan; Liu, Jianping

doi:10.3899/jrheum.210971

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2022

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“…Some others lacked neurological deficits and presented with systemic manifestations such as low-grade fever and weight loss [1,5]. Misdiagnosis is common due to multiple factors such as difficulty in diagnosis, paucity of disease, and variability of clinical presentations [2,5,6]. Imaging is the first step in diagnosis and findings can consist of one or multiple ring-enhancing lesions on computed tomography (CT) or magnetic resonance imaging (MRI) [1,3,7].…”

Section: Introductionmentioning

confidence: 99%

Nocardia Brain Abscess in a Patient With Sarcoidosis

Ghazal¹,

Botchway²,

Naut³

2022

Cureus

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Nocardia species are aerobic, gram-positive, filamentous bacteria. Infection occurs either through inhalation leading to pulmonary symptoms or inoculation presenting with skin findings. Hematogenous dissemination, although uncommon, is possible and can lead to central nervous system involvement. Nocardia brain abscess is a rare manifestation that comprises 2% of all brain abscess etiologies, mostly occurring in immunocompromised patients. Establishing a diagnosis is often difficult, especially due to its rare occurrence and the fact that it can mimic other etiologies on brain imaging including necrotic tumors. High mortality rates have been reported due to delays in establishing a diagnosis and a lack of precise treatment guidelines.

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