Brain Abscess due to Pasteurella multocida

Abstract

The patient was a 26-year-old man who complained of headache and vomiting. On examination, there was nothing abnormal, but the edge of the right optic papilla was not clear. His temperature was 38.5 degrees C, pulse 96/min, blood pressure 120/80 mmHg. A space-occupying lesion in his fronto-dextra cupular part was found by CT scanning. He had a 12-year history of chronic purulent otitis. The diagnosis was a brain abscess in the fronto-dextra cupular part. The brain abscess was extracted and Pasteurella multocida was isolated from the dark brown pus draining from the abscess. The patient recovered through proper antibiotic therapy based on a sensitivity test. Reports of infections caused by this organism in foreign countries very widely from local infections due to bites and scratches by cats, dogs etc. to general infections such as infections of the respiratory tract, sepsis and meningitis. However, Pasteurella multocida brain abscesses are rare. Pasteurella multocida is a Gram-negative short rod which is best known as part of the mouth flora and as a pathogen causing septicemia in many domestic animals, such as cats, dogs etc.. Infection in man results mainly from animal bites or scratches. It has been reported that Pasteurella multodida can cause human septicemia, meningitis, respiratory tract infection, conjunctivitis and other infections. We isolated a strain of Pasteurella multocida from the pus of a brain abscess following chronic purulent otitis on August 6, 1990.

Hematogenous pasteurella haemolytica brain abscess

“…[1,2] Brugnatelli in his study have reported the first human case of Pasteurella infection causing puerperal sepsis in 1913. [1,2] P. multocida is the most frequent human pathogen. Most infections arise from animal bites or scratches and remain localized.…”

“…[1] It is a common cause of infections in animals and rarely causes infections in humans. [1][2][3] The first Pasteurella species was isolated in 1878 by Pasteur in fowl cholera. [1,2] Brugnatelli in his study have reported the first human case of Pasteurella infection causing puerperal sepsis in 1913.…”

“…[1][2][3] The first Pasteurella species was isolated in 1878 by Pasteur in fowl cholera. [1,2] Brugnatelli in his study have reported the first human case of Pasteurella infection causing puerperal sepsis in 1913. [1,2] P. multocida is the most frequent human pathogen.…”

“…Most infections arise from animal bites or scratches and remain localized. [1][2][3][4] Serious deep-seated infections occur occasionally including respiratory tract infections, liver abscess, peritonitis, urinary tract infections, septicemia…, etc. [4] Central nervous system infections occur infrequently; representing less than 5% of non-bite-related cases and are mainly meningitis.…”

Hematogenous pasteurella haemolytica brain abscess

“…[12] Brugnatelli in his study have reported the first human case of Pasteurella infection causing puerperal sepsis in 1913. [12]…”